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Related Party Transactions - Additional Information (Details) - USD ($)
12 Months Ended
May 05, 2020
Dec. 31, 2022
Dec. 31, 2021
Commercial Supply Agreement      
Related Party Transaction [Line Items]      
Agreement extends period for termination 2 years    
Commercial Supply and Temporary Services Agreement      
Related Party Transaction [Line Items]      
Minimum purchase obligation   $ 0  
PCI Pharma Services | Clinical Manufacturing Services      
Related Party Transaction [Line Items]      
Outstanding accounts payable and accrued expenses   1,100,000 $ 1,700,000
Expense related to services   700,000 3,200,000
Takeda | Commercial Supply and Temporary Services Agreement      
Related Party Transaction [Line Items]      
Outstanding accounts payable and accrued expenses   1,400,000 900,000
Expense related to services   $ 1,400,000 $ 1,800,000