Related Party Transactions - Additional Information (Details) - USD ($)		3 Months Ended		6 Months Ended
	May 05, 2020	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021	Dec. 31, 2021
Commercial Supply and Temporary Services Agreement
Related Party Transaction [Line Items]
Minimum purchase obligation		$ 0		$ 0
Commercial Supply Agreement
Related Party Transaction [Line Items]
Agreement extends period for termination	2 years
Frazier
Related Party Transaction [Line Items]
Outstanding accounts payable and accrued expenses		0		0		$ 0
Shared operating expenses		0	$ 0	0	$ 16,000
PCI Pharma Services | Clinical Manufacturing Services
Related Party Transaction [Line Items]
Outstanding accounts payable and accrued expenses		1,200,000		1,200,000		1,700,000
Expense related to services		100,000	700,000	400,000	1,600,000
Takeda | Commercial Supply and Temporary Services Agreement
Related Party Transaction [Line Items]
Outstanding accounts payable and accrued expenses		1,400,000		1,400,000		$ 900,000
Expense related to services		$ 200,000	$ 200,000	$ 1,300,000	$ 200,000