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Related Party Transactions - Additional Information (Details) - USD ($)
3 Months Ended
May 05, 2020
Mar. 31, 2022
Mar. 31, 2021
Dec. 31, 2021
Commercial Supply and Temporary Services Agreement        
Related Party Transaction [Line Items]        
Minimum purchase obligation   $ 0    
Commercial Supply Agreement        
Related Party Transaction [Line Items]        
Agreement extends period for termination 2 years      
Frazier        
Related Party Transaction [Line Items]        
Outstanding accounts payable and accrued expenses   0   $ 0
Shared operating expenses   0 $ 16,000  
PCI Pharma Services | Clinical Manufacturing Services        
Related Party Transaction [Line Items]        
Outstanding accounts payable and accrued expenses   100,000   1,700,000
Expense related to services   300,000 900,000  
Takeda | Commercial Supply and Temporary Services Agreement        
Related Party Transaction [Line Items]        
Outstanding accounts payable and accrued expenses   900,000   $ 900,000
Expense related to services   $ 1,100,000 $ 0