Consolidated Statements of Cash Flows - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023
Operating activities
Net loss	$ (44,485)	$ (45,704)
Reconciliation of net loss to net cash used in operating activities:
Stock-based compensation	4,280	3,335
Non-cash interest expense	486	702
Amortization of premium and interest on marketable securities	(1,450)	(862)
Depreciation expense	24	39
Loss on extinguishment of debt	942	0
Changes in operating assets and liabilities:
Prepaid expenses and other assets	3,517	(2,143)
Accounts payable	52	(5,855)
Accrued expenses	270	(5,692)
Net cash used in operating activities	(36,364)	(56,180)
Investing activities
Purchase of marketable securities	(69,565)	(42,657)
Proceeds from sales and maturities of marketable securities	61,200	54,200
Net cash (used in) provided by investing activities	(8,365)	11,543
Financing activities
Proceeds from issuance of common stock upon at-the-market offering, net of issuance costs	44,207	0
Proceeds from issuance of common stock, purchase warrants and pre-funded warrants for the purchase of common stock, net of underwriting discounts, commissions, and offering costs	0	46,503
Proceeds from issuance of common stock upon stock option exercises	499	1,496
Proceeds from issuance of common stock upon exercise of common warrants	450	0
Common stock repurchase	(48)	(24)
Payment of debt extinguishment costs	(170)	0
Net cash provided by financing activities	44,938	47,975
Net increase in cash and cash equivalents	209	3,338
Cash and cash equivalents, beginning of year	49,255	45,917
Cash and cash equivalents, end of year	49,464	49,255
Supplemental disclosure of cash flow information
Interest paid	3,533	3,164
Cash paid for taxes	$ 47	$ 26