Accrued Expenses - Schedule (Details) - USD ($) $ in Thousands	Mar. 31, 2023	Dec. 31, 2022
Accrued Expenses
Accrued preclinical and clinical trial costs	$ 4,724	$ 6,174
Accrued restructuring charges	3,401	0
Accrued compensation	701	2,498
Accrued consulting	171	75
Accrued professional services	108	218
Accrued other	386	365
Total accrued expenses	$ 9,491	$ 9,330