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Subsequent Events (Details) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 6 Months Ended
Jul. 31, 2022
Jun. 30, 2022
Jun. 30, 2021
Dec. 31, 2021
Subsequent Events        
Gross proceeds   $ 0 $ 91,977  
Common stock, par value   $ 0.0001   $ 0.0001
Subsequent Events | K2 HealthVentures LLC        
Subsequent Events        
Number of shares purchased by warrants 339,725      
Warrants exercise price $ 1.3246      
Subsequent Events | K2 HealthVentures LLC | Term loan        
Subsequent Events        
Principal amount $ 50,000      
Interest only payments term 30 months      
Interest rate (as a percent) 7.95%      
Threshold interest rate 3.20%      
End of term charge (as a percent) 6.45%      
Principal amount for debt conversion $ 3,250      
Common stock, par value $ 0.0001      
Conversion price $ 2.6493      
Nasdaq beneficial ownership limitations, percentage 19.99%      
Subsequent Events | K2 HealthVentures LLC | Term loan tranche one        
Subsequent Events        
Principal amount $ 30,000      
Subsequent Events | K2 HealthVentures LLC | Term loan tranche two        
Subsequent Events        
Principal amount 20,000      
Subsequent Events | K2 HealthVentures LLC | Minimum | Term loan        
Subsequent Events        
Cash, cash equivalents and marketable securities balances to be maintained 25,000      
Subsequent Events | K2 HealthVentures LLC | Maximum        
Subsequent Events        
Investment from lenders in future equity financings $ 5,000      
Percent of equity investment from lenders 10.00%      
Subsequent Events | K2 HealthVentures LLC | Maximum | Term loan        
Subsequent Events        
Total market capitalization $ 250,000      
Subsequent Events | License Agreement | CSPC Megalith Biopharmaceutical Co., Ltd        
Subsequent Events        
Upfront license fee $ 27,000      
Term of agreement (in years) 10 years      
Number of days written prior notice to terminate agreement 180 days      
Subsequent Events | License Agreement | CSPC Megalith Biopharmaceutical Co., Ltd | Maximum        
Subsequent Events        
Development and regulatory milestone payments $ 148,000      
Commercial milestone payments 1,000,000      
Payments as percentage of non-royalty sublicense income 50,000      
Subsequent Events | At-The-Market offering | Cowen and Company, LLC        
Subsequent Events        
Gross proceeds $ 50,000      
Commission on sale of common stock (as a percent) 3.00%