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Segment Information (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Consolidated Statements of Comprehensive Income/(Loss)      
Contract revenue $ 8,341 $ 8,688 $ 16,371
Grant revenue 3,427 1,119 4,377
Total revenue 11,768 9,807 20,748
General and administrative expenses 49,440 59,358 47,365
Research and development expenses 81,859 85,848 77,402
Total operating expense 131,299 145,206 124,767
Other income/(expense):      
Gain on deconsolidation 0 264,409 41,730
Loss realized on sale of investments (54,976) 0 0
Gain/(loss) on disposal of assets (30) (82) 4,060
Gain on loss of significant influence 0 445,582 10,287
Other income/(expense) 1,065 121 (278)
Other income/(expense) 178,732 672,167 21,154
Net finance income/(costs) (6,115) (46,147) 25,917
Share of net income/(loss) of associates accounted for using the equity method (34,117) 30,791 (11,490)
Income/(loss) before taxes 18,969 478,474 (68,438)
Finance income/(costs) – subsidiary preferred shares 0 (1,458) (106)
Share-based payment expense 10,718 14,468 12,637
Depreciation of tangible assets 3,900 3,200 2,500
Amortization of ROU assets (2,699) (3,237)  
Amortization of intangible assets 0 100 300
Taxation (14,401) (112,409) (2,221)
Income/(loss) for the year 4,568 366,065 (70,659)
Other comprehensive income 469 (10) (240)
Total comprehensive income/(loss) for the year 5,037 366,055 (70,899)
Total comprehensive income/(loss) attributable to:      
Owners of the Company 6,454 421,134 (43,894)
Non-controlling interests (1,417) (55,079) (27,005)
Consolidated Statements of Financial Position      
Total assets 989,994 941,178  
Total liabilities 336,455 290,780  
Internal      
Consolidated Statements of Comprehensive Income/(Loss)      
Contract revenue 3,560 6,064 2,110
Grant revenue 32 15 86
Total revenue 3,592 6,079 2,195
General and administrative expenses (2,112) (2,385) (1,498)
Research and development expenses (41,583) (25,977) (8,929)
Total operating expense (43,695) (28,362) (10,427)
Other income/(expense):      
Gain on deconsolidation   0 0
Gain/(loss) on investments held at fair value 0 0 0
Loss realized on sale of investments 0    
Gain/(loss) on disposal of assets (15) 17 0
Gain on loss of significant influence   0 0
Other income/(expense) 0 0 0
Other income/(expense) (15) 17 0
Net finance income/(costs) 19 0
Share of net income/(loss) of associates accounted for using the equity method 0 0 0
Impairment of investment in associate   0  
Income/(loss) before taxes (40,098) (22,266) (8,232)
(Loss)/income before taxes pre IAS 39 fair value accounting, finance costs – subsidiary preferred shares, share-based payment expense, depreciation of tangible assets and amortization of intangible assets     (8,210)
Income/(loss) before taxes pre IFRS 9 fair value accounting, finance costs – subsidiary preferred shares, share-based payment expense, depreciation of tangible assets and amortization of intangible assets (36,770) (21,889)  
Finance income/(costs) – subsidiary preferred shares 0 0 0
Finance income/(costs) – IFRS 9 fair value accounting 0 0  
Finance income/(costs) – IAS 39 fair value accounting     0
Share-based payment expense (2,491) (5) (11)
Depreciation of tangible assets (838) (376) (7)
Amortization of ROU assets 0 0  
Amortization of intangible assets 0 4 (4)
Taxation 0 0 0
Income/(loss) for the year (40,098) (22,266) (8,454)
Other comprehensive income 0 0 0
Total comprehensive income/(loss) for the year (40,098) (22,266) (8,454)
Total comprehensive income/(loss) attributable to:      
Owners of the Company (40,098) (7,002) (1,139)
Non-controlling interests 0 (15,264) (7,315)
Consolidated Statements of Financial Position      
Total assets 87,917 17,614 2,984
Total liabilities 117,964 12,076 13,366
Net assets/(liabilities) (30,047) 5,538 (10,381)
Controlled Founded Entities      
Consolidated Statements of Comprehensive Income/(Loss)      
Contract revenue 2,726 2,487 14,233
Grant revenue 3,395 1,104 4,271
Total revenue 6,121 3,591 18,504
General and administrative expenses (15,061) (14,436) (10,212)
Research and development expenses (40,043) (42,780) (36,930)
Total operating expense (55,104) (57,216) (47,142)
Other income/(expense):      
Gain on deconsolidation   0 0
Gain/(loss) on investments held at fair value 0 0 0
Loss realized on sale of investments 0    
Gain/(loss) on disposal of assets (15) (39) 0
Gain on loss of significant influence   0 0
Other income/(expense) 100 166
Other income/(expense) 85 127 0
Net finance income/(costs) (5,204) (16,947) 5,341
Share of net income/(loss) of associates accounted for using the equity method 0 0 0
Impairment of investment in associate   0  
Income/(loss) before taxes (54,102) (70,445) (23,297)
(Loss)/income before taxes pre IAS 39 fair value accounting, finance costs – subsidiary preferred shares, share-based payment expense, depreciation of tangible assets and amortization of intangible assets     (24,344)
Income/(loss) before taxes pre IFRS 9 fair value accounting, finance costs – subsidiary preferred shares, share-based payment expense, depreciation of tangible assets and amortization of intangible assets (44,181) (48,996)  
Finance income/(costs) – subsidiary preferred shares 0 107 0
Finance income/(costs) – IFRS 9 fair value accounting (4,351) (17,294)  
Finance income/(costs) – IAS 39 fair value accounting     5,341
Share-based payment expense (2,822) (1,678) (2,465)
Depreciation of tangible assets (1,560) (1,531) (1,823)
Amortization of ROU assets (1,186) (1,060)  
Amortization of intangible assets (1) 7 (6)
Taxation (1) (134) (381)
Income/(loss) for the year (54,103) (70,579) (26,206)
Other comprehensive income 0 0 (214)
Total comprehensive income/(loss) for the year (54,103) (70,579) (26,420)
Total comprehensive income/(loss) attributable to:      
Owners of the Company (52,701) (54,717) (15,710)
Non-controlling interests (1,402) (15,862) (10,710)
Consolidated Statements of Financial Position      
Total assets 68,731 41,612 15,603
Total liabilities 212,542 132,935 60,992
Net assets/(liabilities) (143,812) (91,324) (45,389)
Non-Controlled Founded Entities      
Consolidated Statements of Comprehensive Income/(Loss)      
Contract revenue 0 0 0
Grant revenue 0 0 20
Total revenue 0 0 20
General and administrative expenses 0 (10,439) (16,385)
Research and development expenses 0 (15,555) (29,851)
Total operating expense 0 (25,994) (46,236)
Other income/(expense):      
Gain on deconsolidation   0 0
Gain/(loss) on investments held at fair value 0 0 0
Loss realized on sale of investments 0    
Gain/(loss) on disposal of assets 0 0 0
Gain on loss of significant influence   0 0
Other income/(expense) 0 0 104
Other income/(expense) 0 0 104
Net finance income/(costs) 0 (30,141) 5,945
Share of net income/(loss) of associates accounted for using the equity method 0 0 0
Impairment of investment in associate   0  
Income/(loss) before taxes 0 (56,135) (40,167)
(Loss)/income before taxes pre IAS 39 fair value accounting, finance costs – subsidiary preferred shares, share-based payment expense, depreciation of tangible assets and amortization of intangible assets     (38,761)
Income/(loss) before taxes pre IFRS 9 fair value accounting, finance costs – subsidiary preferred shares, share-based payment expense, depreciation of tangible assets and amortization of intangible assets 0 (21,873)  
Finance income/(costs) – subsidiary preferred shares 0 (1,564) 0
Finance income/(costs) – IFRS 9 fair value accounting 0 (28,737)  
Finance income/(costs) – IAS 39 fair value accounting     5,516
Share-based payment expense 0 (3,543) (6,262)
Depreciation of tangible assets 0 (207) (390)
Amortization of ROU assets 0 (83)  
Amortization of intangible assets 0 (128) (270)
Taxation 0 (162) (185)
Income/(loss) for the year 0 (56,297) (41,239)
Other comprehensive income 0 (10) 0
Total comprehensive income/(loss) for the year 0 (56,307) (41,239)
Total comprehensive income/(loss) attributable to:      
Owners of the Company 0 (32,353) (32,260)
Non-controlling interests 0 (23,953) (8,980)
Consolidated Statements of Financial Position      
Total assets 0 0 35,934
Total liabilities 0 0 202,161
Net assets/(liabilities) 0 0 (166,227)
Parent Company And Other      
Consolidated Statements of Comprehensive Income/(Loss)      
Contract revenue 2,054 137 29
Grant revenue 0 0 0
Total revenue 2,054 137 29
General and administrative expenses (32,267) (32,098) (19,270)
Research and development expenses (234) (1,536) (1,692)
Total operating expense (32,500) (33,634) (20,962)
Other income/(expense):      
Gain on deconsolidation   264,409 41,730
Gain/(loss) on investments held at fair value 232,674 (37,863) (34,615)
Loss realized on sale of investments (54,976)    
Gain/(loss) on disposal of assets 0 (60) 4,054
Gain on loss of significant influence   445,582 10,287
Other income/(expense) 965 (45) (405)
Other income/(expense) 178,662 672,023 21,051
Net finance income/(costs) (930) 941 14,631
Share of net income/(loss) of associates accounted for using the equity method (34,117) 30,791 (11,490)
Impairment of investment in associate   42,938  
Income/(loss) before taxes 113,170 627,320 3,258
(Loss)/income before taxes pre IAS 39 fair value accounting, finance costs – subsidiary preferred shares, share-based payment expense, depreciation of tangible assets and amortization of intangible assets     (4,235)
Income/(loss) before taxes pre IFRS 9 fair value accounting, finance costs – subsidiary preferred shares, share-based payment expense, depreciation of tangible assets and amortization of intangible assets 121,644 640,298  
Finance income/(costs) – subsidiary preferred shares 0 (1) (106)
Finance income/(costs) – IFRS 9 fair value accounting 0 (444)  
Finance income/(costs) – IAS 39 fair value accounting     11,775
Share-based payment expense (5,405) (9,242) (3,899)
Depreciation of tangible assets (1,547) (1,114) (256)
Amortization of ROU assets (1,523) (2,177)  
Amortization of intangible assets 0 0 (22)
Taxation (14,400) (112,113) (1,655)
Income/(loss) for the year 98,769 515,207 5,239
Other comprehensive income 469 0 (26)
Total comprehensive income/(loss) for the year 99,238 515,207 5,213
Total comprehensive income/(loss) attributable to:      
Owners of the Company 99,253 515,207 5,213
Non-controlling interests (15) 0 0
Consolidated Statements of Financial Position      
Total assets 833,347 881,952 387,240
Total liabilities 5,949 145,768 (1,731)
Net assets/(liabilities) 827,397 736,184 388,970
Operating segments [member]      
Consolidated Statements of Comprehensive Income/(Loss)      
Contract revenue 8,341 8,688 16,371
Grant revenue 3,427 1,119 4,377
Total revenue 11,768 9,807 20,748
General and administrative expenses (49,440) (59,358) (47,365)
Research and development expenses (81,859) (85,848) (77,402)
Total operating expense (131,299) (145,206) (124,768)
Other income/(expense):      
Gain on deconsolidation   264,409 41,730
Gain/(loss) on investments held at fair value 232,674 (37,863) (34,615)
Loss realized on sale of investments (54,976)    
Gain/(loss) on disposal of assets (30) (82) 4,054
Gain on loss of significant influence   445,582 10,287
Other income/(expense) 1,065 121 (302)
Other income/(expense) 178,732 672,167 21,155
Net finance income/(costs) (6,115) (46,147) 25,918
Share of net income/(loss) of associates accounted for using the equity method (34,117) 30,791 (11,490)
Impairment of investment in associate   42,938  
Income/(loss) before taxes 18,969 478,474 (68,438)
(Loss)/income before taxes pre IAS 39 fair value accounting, finance costs – subsidiary preferred shares, share-based payment expense, depreciation of tangible assets and amortization of intangible assets     (75,550)
Income/(loss) before taxes pre IFRS 9 fair value accounting, finance costs – subsidiary preferred shares, share-based payment expense, depreciation of tangible assets and amortization of intangible assets 40,694 547,540  
Finance income/(costs) – subsidiary preferred shares 0 (1,458) (106)
Finance income/(costs) – IFRS 9 fair value accounting (4,351) (46,475)  
Finance income/(costs) – IAS 39 fair value accounting     22,632
Share-based payment expense (10,718) (14,468) (12,637)
Depreciation of tangible assets (3,945) (3,228) (2,476)
Amortization of ROU assets (2,709) (3,320)  
Amortization of intangible assets (1) (117) (302)
Taxation (14,401) (112,409) (2,221)
Income/(loss) for the year 4,568 366,065 (70,659)
Other comprehensive income 469 (10) (240)
Total comprehensive income/(loss) for the year 5,037 366,055 (70,899)
Total comprehensive income/(loss) attributable to:      
Owners of the Company 6,454 421,133 (43,894)
Non-controlling interests (1,417) (55,079) (27,005)
Consolidated Statements of Financial Position      
Total assets 989,994 941,178 441,761
Total liabilities 336,455 290,779 274,787
Net assets/(liabilities) $ 653,539 $ 650,399 $ 166,973