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Note 5 - Balance Sheet Components (10 Q) (Details Textual) - USD ($)
3 Months Ended 12 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Dec. 31, 2022
Dec. 31, 2021
Gain (Loss) on Disposition of Property Plant Equipment $ 16,000 $ (0)    
Depreciation 17,000 $ 28,000 $ 110,000 $ 105,000
Laboratory Equipment [Member]        
Property, Plant and Equipment, Disposals 150,000      
Gain (Loss) on Disposition of Property Plant Equipment $ 16,000