<SEC-DOCUMENT>0000950170-25-059573-index.html : 20250429
<SEC-HEADER>0000950170-25-059573.hdr.sgml : 20250429
<ACCEPTANCE-DATETIME>20250429074102
ACCESSION NUMBER:		0000950170-25-059573
CONFORMED SUBMISSION TYPE:	DEF 14A
PUBLIC DOCUMENT COUNT:		8
CONFORMED PERIOD OF REPORT:	20250429
FILED AS OF DATE:		20250429
DATE AS OF CHANGE:		20250429

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Pyxis Oncology, Inc.
		CENTRAL INDEX KEY:			0001782223
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				831160910
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		DEF 14A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-40881
		FILM NUMBER:		25882701

	BUSINESS ADDRESS:	
		STREET 1:		321 HARRISON AVENUE
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02118
		BUSINESS PHONE:		(617) 221-9059

	MAIL ADDRESS:	
		STREET 1:		321 HARRISON AVENUE
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02118
</SEC-HEADER>
<DOCUMENT>
<TYPE>DEF 14A
<SEQUENCE>1
<FILENAME>2025_pyxs-14a.htm
<DESCRIPTION>DEF 14A
<TEXT>
Document 1 - file: 2025_pyxs-14a.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>img179289491_0.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 2 - file: img179289491_0.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>img179289491_1.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 3 - file: img179289491_1.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>img179289491_2.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: img179289491_2.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>img179289491_3.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 5 - file: img179289491_3.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>img179289491_4.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 6 - file: img179289491_4.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>img179289491_5.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 7 - file: img179289491_5.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>8
<FILENAME>img179289491_6.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 8 - file: img179289491_6.jpg

</DOCUMENT>
</SEC-DOCUMENT>