XML 42 R30.htm IDEA: XBRL DOCUMENT v3.22.1
License Agreements - Additional Information (Details) - USD ($)
1 Months Ended 3 Months Ended
Mar. 28, 2022
Apr. 30, 2022
Dec. 31, 2020
Apr. 30, 2020
Mar. 31, 2022
Mar. 31, 2021
Jan. 31, 2022
Jan. 31, 2021
Research And Development Arrangement Contract To Perform For Others [Line Items]                
Research and development expense         $ 20,071,000 $ 32,774,000    
Proceeds from stock options exercised         176,000      
Pfizer License Agreement                
Research And Development Arrangement Contract To Perform For Others [Line Items]                
Research and development expense           25,000,000.0    
Milestone and royalties incurred         0      
Upfront payments           $ 5,000,000.0    
Pfizer License Agreement | Series B Convertible Preferred Stock                
Research And Development Arrangement Contract To Perform For Others [Line Items]                
Issuance of convertible preferred stock shares           12,152,145    
Issuance of convertible preferred stock value           $ 20,000,000.0   $ 20,000,000.0
Pfizer License Agreement | Research and Development Expenses                
Research And Development Arrangement Contract To Perform For Others [Line Items]                
Payment for license fee           25,000,000.0    
LegoChem License Agreement                
Research And Development Arrangement Contract To Perform For Others [Line Items]                
Payments to purchase licensed products           9,000,000.0    
Proceeds from stock options exercised     $ 8,000,000.0          
Extra milestone payment     $ 9,600,000          
Derivative liability           3,400,000 $ 9,600,000 $ 3,400,000
Fair value adjustment to the derivative liability           $ 1,100,000    
Other milestone and royalties incurred         0      
Biosion License Agreement                
Research And Development Arrangement Contract To Perform For Others [Line Items]                
Research and development expense         10,000,000      
Milestone and royalties incurred         $ 0      
Royalty obligation period for licensed products upon first commercial sale 12 years              
Biosion License Agreement | Subsequent Event                
Research And Development Arrangement Contract To Perform For Others [Line Items]                
Upfront fee   $ 10,000,000            
Aggregate maximum obligation to pay future contingent milestone payments for normal approval   217,500,000            
Aggregate maximum obligation to pay future contingent milestone payments for accelerated approval   $ 222,500,000            
University License Agreement                
Research And Development Arrangement Contract To Perform For Others [Line Items]                
Stock issued       48,919        
Milestone and royalties incurred             $ 0