Related Parties - Additional Information (Details) - USD ($)	1 Months Ended		12 Months Ended
	Mar. 31, 2021	Apr. 30, 2020	Dec. 31, 2021	Dec. 31, 2020
Related Party Transaction [Line Items]
Research and development expense			$ 51,054,000	$ 9,048,000
Pfizer License Agreement
Related Party Transaction [Line Items]
Research and development expense			25,000,000.0
Upfront payments			5,000,000.0
LegoChem License Agreement
Related Party Transaction [Line Items]
Research and development expense			$ 0
Upfront payments	$ 500,000			$ 5,000,000.0
Common Stock
Related Party Transaction [Line Items]
Stock issued				49,061
Series B Convertible Preferred Stock | Pfizer License Agreement
Related Party Transaction [Line Items]
Issuance of convertible preferred stock shares			12,152,145
Issuance of convertible preferred stock value			$ 20,000,000.0
Series B Convertible Preferred Stock | LegoChem License Agreement
Related Party Transaction [Line Items]
Issuance of convertible preferred stock shares	303,804
University License Agreement
Related Party Transaction [Line Items]
Stock issued		48,919
Research and development expense			0	$ 3,000
University License Agreement | Common Stock
Related Party Transaction [Line Items]
Stock issued		48,919
University License Agreement | Series A Preferred Stock
Related Party Transaction [Line Items]
Stock issued				309,885
Scientific Advisory Board
Related Party Transaction [Line Items]
Maximum amount paid to board members			100,000	$ 100,000
Aggregate maximum amount paid to related parties			100,000	100,000
Voxall
Related Party Transaction [Line Items]
Contributed amount to joint venture by each member			50,000
Recognized service fee as other income			$ 181,000
Minimum | Scientific Advisory Board
Related Party Transaction [Line Items]
Payments to board members per month				3,000
Maximum | Scientific Advisory Board
Related Party Transaction [Line Items]
Payments to board members per month				$ 5,000