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Income Taxes - Reconciliation of Federal Statutory Income Tax Rate to Effective Income Tax Rate (Details)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Income Tax Disclosure [Abstract]    
Income tax computed at federal statutory rate% 21.00% 21.00%
State taxes, net of federal benefit 5.70% 5.60%
Change in valuation allowance (27.70%) (27.90%)
Research and development credit carryovers 1.90% 1.50%
Permanent differences (0.90%) (0.20%)
Effective income tax rate% 0.00% 0.00%