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Document and Entity Information - USD ($)
$ in Millions
 12 Months Ended
Dec. 31, 2024
Mar. 25, 2025
Jun. 28, 2024
Document and Entity Information      
Document Type 10-K    
Document Annual Report true    
Document Period End Date Dec. 31, 2024    
Document Transition Report false    
Entity File Number 001-39069    
Entity Registrant Name Aprea Therapeutics, Inc.    
Entity Incorporation, State or Country Code DE    
Entity Tax Identification Number 84-2246769    
Entity Address, Address Line One 3805 Old Easton Road    
Entity Address, City or Town Doylestown    
Entity Address, State or Province PA    
Entity Address, Postal Zip Code 18902    
City Area Code 215    
Local Phone Number 948-4119    
Title of 12(b) Security Common stock, par value $0.001 per share    
Trading Symbol APRE    
Security Exchange Name NASDAQ    
Entity Well Known Seasoned Issuer No    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity Filer Category Non-accelerated Filer    
Entity Small Business true    
Entity Emerging Growth Company false    
ICFR Auditor Attestation Flag false    
Entity Shell Company false    
Document Financial Statement Error Correction [Flag] false    
Entity Public Float     $ 10.0
Entity Common Stock, Shares Outstanding   5,491,953  
Documents Incorporated by Reference

Portions of the registrant’s definitive proxy statement for its 2024 Annual Meeting of Stockholders (the “Proxy Statement”), to be filed within 120 days of the registrant’s fiscal year ended December 31, 2024, are incorporated by reference in Part III of this Annual Report on Form 10-K. Except with respect to information specifically incorporated by reference in this Annual Report on Form 10-K, the Proxy Statement is not deemed to be filed as part of this Annual Report on Form 10-K.

    
Entity Central Index Key 0001781983    
Current Fiscal Year End Date --12-31    
Document Fiscal Year Focus 2024    
Document Fiscal Period Focus FY    
Amendment Flag false    
Auditor Name EisnerAmper LLP    
Auditor Firm ID 274    
Auditor Location Philadelphia, Pennsylvania