Nature of business and basis of presentation (Details)			1 Months Ended	12 Months Ended
	Feb. 10, 2023	May 16, 2022 USD ($) $ / shares shares	Mar. 31, 2024 USD ($)	Dec. 31, 2023 USD ($) $ / shares	Dec. 31, 2022 USD ($) $ / shares	Dec. 31, 2021 USD ($)
Common stock, par value (in dollars per share) | $ / shares				$ 0.001	$ 0.001
Reverse stock split ratio	0.05
Cash balance				$ 21,606,820	$ 28,786,647	$ 53,076,052
Common stock issuance costs				$ 648,928
Subsequent Event
Proceeds from sale of common stock in a private placement			$ 16,000,000
Common stock issuance costs			$ 1,400,000
Atrin Pharmaceuticals, Inc
Number of shares to purchase under option | shares		163,757
Cash balance		$ 2,489,745
Common Stock | Atrin Pharmaceuticals, Inc
Issuance of stock upon acquisition of Atrin (in shares). | shares		55,869
Common stock, par value (in dollars per share) | $ / shares		$ 0.001
Series A Convertible Preferred Stock | Atrin Pharmaceuticals, Inc
Issuance of stock upon acquisition of Atrin (in shares). | shares		2,949,630
Conversion value		$ 68,800,000
Preferred stock conversion ratio		10