Stockholders' equity (Details)			1 Months Ended		3 Months Ended
	May 16, 2022 $ / shares shares	Nov. 12, 2020 USD ($)	Feb. 28, 2023 USD ($) $ / shares shares	Feb. 28, 2022 USD ($)	Mar. 31, 2023 USD ($) Vote $ / shares shares	Mar. 31, 2022 USD ($) shares	Dec. 31, 2022 $ / shares shares
Common stock
Stock, shares authorized					440,000,000
Common stock, shares authorized					400,000,000		400,000,000
Common stock, par value (in dollars per share) | $ / shares					$ 0.001		$ 0.001
Preferred stock, shares authorized					40,000,000
Preferred stock, par value (in dollars per share) | $ / shares					$ 0.001
Commission payable as a percentage of gross proceeds from sale of common stock under ATM offering		3.00%
Number of voting rights per common share | Vote					1
Stock based compensation expense | $					$ 16,244	$ 2,100,000
Shelf Registration Statement
Maximum amount to be issued under universal shelf registration statement | $		$ 350,000,000.0
Maximum amount to be issued under at-the-market offering program | $		$ 14,744,728
Proceeds from issuance of common stock | $					5,788,918
Common stock issuance costs | $					$ 648,928
Common Stock
Common stock
Conversion of preferred stock into common stock (in shares)					1,446,701
Shelf Registration Statement
Shares issued			1,050,000
Issue price per share | $ / shares			$ 5.25
Proceeds from issuance of common stock | $			$ 4,900,000
Common stock issuance costs | $				$ 600,000
Series A Convertible Preferred Stock
Common stock
Conversion of preferred stock into common stock (in shares)					2,893,403
Number of shares remained to be converted into common stock					56,227
Atrin Pharmaceuticals, Inc | Common Stock
Common stock
Common stock, par value (in dollars per share) | $ / shares	$ 0.001
Issuance of stock upon acquisition of Atrin (in shares)	55,869
Atrin Pharmaceuticals, Inc | Series A Convertible Preferred Stock
Common stock
Issuance of stock upon acquisition of Atrin (in shares)	2,949,630
Preferred stock conversion ratio	10
ATM offering
Shelf Registration Statement
Shares issued					26,302	0
Proceeds from issuance of common shares | $					$ 300,000
Common stock issuance costs | $						$ 8,000