Property and equipment (Details) - USD ($)	12 Months Ended
Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Property and equipment
Property and equipment, at cost	$ 45,391	$ 140,877
Less accumulated depreciation and amortization	(43,070)	(117,007)
Property and equipment-net	2,321	23,870
Depreciation expense	4,403	12,829	$ 28,834
Lab equipment
Property and equipment
Property and equipment, at cost	40,133	90,770
Furniture and fixtures
Property and equipment
Property and equipment, at cost		31,152
Computer equipment
Property and equipment
Property and equipment, at cost	$ 5,258	$ 18,955

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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- Definition

The aggregate expense recognized in the current period that allocates the cost of tangible assets, intangible assets, or depleting assets to periods that benefit from use of the assets.

+ References

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Amount before accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

+ References

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Amount after accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business to produce goods and services and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

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