<SEC-DOCUMENT>0001558370-22-014939-index.html : 20221011
<SEC-HEADER>0001558370-22-014939.hdr.sgml : 20221011
<ACCEPTANCE-DATETIME>20221011170019
ACCESSION NUMBER:		0001558370-22-014939
CONFORMED SUBMISSION TYPE:	PRE 14A
PUBLIC DOCUMENT COUNT:		7
CONFORMED PERIOD OF REPORT:	20221116
FILED AS OF DATE:		20221011
DATE AS OF CHANGE:		20221011

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Aprea Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001781983
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		PRE 14A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-39069
		FILM NUMBER:		221304648

	BUSINESS ADDRESS:	
		STREET 1:		535 BOYLSTON STREET
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02116
		BUSINESS PHONE:		6095104718

	MAIL ADDRESS:	
		STREET 1:		535 BOYLSTON STREET
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02116
</SEC-HEADER>
<DOCUMENT>
<TYPE>PRE 14A
<SEQUENCE>1
<FILENAME>tmb-20221116xpre14a.htm
<DESCRIPTION>PRE 14A
<TEXT>
Document 1 - file: tmb-20221116xpre14a.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>tmb-20221116xpre14a008.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 2 - file: tmb-20221116xpre14a008.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>tmb-20221116xpre14a006.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 3 - file: tmb-20221116xpre14a006.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>tmb-20221116xpre14a009.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: tmb-20221116xpre14a009.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>tmb-20221116xpre14a005.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 5 - file: tmb-20221116xpre14a005.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>tmb-20221116xpre14a001.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 6 - file: tmb-20221116xpre14a001.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>tmb-20221116xpre14a004.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 7 - file: tmb-20221116xpre14a004.jpg

</DOCUMENT>
</SEC-DOCUMENT>