Stock option plans - Stock option activity (Details) - 2019 Equity Incentive Plan - USD ($)	12 Months Ended
Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019	Dec. 31, 2018
Number of options
Outstanding, beginning of period	3,771,459	3,499,934	1,844,188
Granted	1,179,650	446,800	2,018,796
Exercised	(226,394)	(164,075)	(322,267)
Cancelled/Forfeited	(138,100)	(11,200)	(40,783)
Outstanding, end of period	4,586,615	3,771,459	3,499,934	1,844,188
Exercisable	2,518,554
Vested or expected to vest	4,586,615
Weighted average exercise price per share
Outstanding, beginning of period	$ 9.10	$ 5.49	$ 0.82
Granted	5.87	35.51	8.82
Exercised	0.92	0.92	0.23
Cancelled/Forfeited	16.53	38.78	0.99
Outstanding, end of period	8.45	$ 9.10	$ 5.49	$ 0.82
Exercisable	6.89
Vested or expected to vest	$ 8.45
Weighted average remaining contractual term (in years)
Outstanding	6 years 7 months 6 days	6 years 9 months 18 days	7 years 6 months	7 years 7 months 6 days
Exercisable	5 years 6 months
Vested or expected to vest	6 years 7 months 6 days
Aggregate Intrinsic Value
Outstanding	$ 2,101,398
Exercisable	2,093,937
Vested or expected to vest	$ 2,101,398
Additional Disclosures
Weighted average grant date fair value of options granted	$ 4.29	$ 24.20	$ 6.68

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