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Consolidated Statements of Operations and Comprehensive Loss - USD ($)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Operating expenses:      
Research and development $ 23,895,875 $ 37,879,325 $ 20,950,672
General and administrative 13,550,478 14,931,887 8,593,626
Total operating expenses 37,446,353 52,811,212 29,544,298
Other income (expense):      
Interest income, net 1,648 222,652 156,351
Foreign currency gain (loss) 317,402 (890,252) 1,328,140
Total other income (expense) 319,050 (667,600) 1,484,491
Net loss (37,127,303) (53,478,812) (28,059,807)
Other comprehensive loss:      
Foreign currency translation (321,695) 1,496,517 (2,772,453)
Total comprehensive loss $ (37,448,998) $ (51,982,295) $ (30,832,260)
Net loss per share attributable to common stockholders, basic (in dollars per share) $ (1.74) $ (2.53) $ (4.67)
Net loss per share attributable to common stockholders, diluted (in dollars per share) $ (1.74) $ (2.53) $ (4.67)
Weighted-average common shares outstanding, basic (in shares) 21,286,547 21,133,651 6,002,486
Weighted-average common shares outstanding, diluted (in shares) 21,286,547 21,133,651 6,002,486