Income taxes (Tables)

12 Months Ended

Dec. 31, 2019

Income Taxes

Schedule of components of the net loss

	Year ended December 31,
	2019		2018		2017
Foreign	$	(25,268,373)	$	(15,713,032)	$	(15,185,931)
Domestic		(2,791,434)		184,763		(4,319)
Net loss	$	(28,059,807)	$	(15,528,269)	$	(15,190,250)

Summary of reconciliation of the effect of applying federal statutory rate to the net loss and the effective income tax rate

	Year ended December 31,
	2019		2018		2017
Statutory federal income tax rate	21.0	%	21.0	%	34.0	%
Earnings in jurisdictions taxed at rates different from the statutory U.S. federal tax rate	0.4	%	1.0	%	(12.0)	%
Permanent differences	3.7	%	0.4	%	(0.1)	%
Changes in valuation allowance	(25.1)	%	(16.7)	%	(21.5)	%
Rate change due to TCJA	—	%	—	%	(0.4)	%
Rate change due to Swedish tax reform	—	%	(5.7)	%	—	%
Effective income tax rate	—	%	—	%	—	%

Summary of significant components of deferred taxes

	December 31,
	2019		2018
Deferred tax assets:
Net operating loss carryforward	$	20,536,344	$	12,816,395
Capitalized research and development		—		1,951
Intangible assets		26,842		—
Accrued expenses		17,779		—
Lease liability - ASC 842		128,337		—
Gross deferred tax assets		20,709,302		12,818,346
Valuation allowance		(19,676,794)		(12,661,874)
Total deferred tax assets		1,032,508		156,472
Deferred tax liabilities:
Fixed assets		(1,692)		(2,050)
Stock Compensation		(908,322)		(154,422)
Right of Use Asset - ASC 842		(122,494)		—
Total deferred tax liabilities		(1,032,508)		(156,472)
Net deferred tax assets (liabilities)	$	—	$	—