<SEC-DOCUMENT>0001104659-24-043099-index.html : 20240403
<SEC-HEADER>0001104659-24-043099.hdr.sgml : 20240403
<ACCEPTANCE-DATETIME>20240403160640
ACCESSION NUMBER:		0001104659-24-043099
CONFORMED SUBMISSION TYPE:	S-3
PUBLIC DOCUMENT COUNT:		6
FILED AS OF DATE:		20240403
DATE AS OF CHANGE:		20240403

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Aprea Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001781983
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-3
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-278485
		FILM NUMBER:		24818723

	BUSINESS ADDRESS:	
		STREET 1:		3805 OLD EASTON ROAD
		CITY:			DOYLESTOWN
		STATE:			PA
		ZIP:			18902
		BUSINESS PHONE:		617-463-9385

	MAIL ADDRESS:	
		STREET 1:		3805 OLD EASTON ROAD
		CITY:			DOYLESTOWN
		STATE:			PA
		ZIP:			18902
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-3
<SEQUENCE>1
<FILENAME>tm2410156-1_s3.htm
<DESCRIPTION>S-3
<TEXT>
Document 1 - file: tm2410156-1_s3.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>2
<FILENAME>tm2410156d2_ex5-1.htm
<DESCRIPTION>EXHIBIT 5.1
<TEXT>
Document 2 - file: tm2410156d2_ex5-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.2
<SEQUENCE>3
<FILENAME>tm2410156d2_ex23-2.htm
<DESCRIPTION>EXHIBIT 23.2
<TEXT>
Document 3 - file: tm2410156d2_ex23-2.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.3
<SEQUENCE>4
<FILENAME>tm2410156d2_ex23-3.htm
<DESCRIPTION>EXHIBIT 23.3
<TEXT>
Document 4 - file: tm2410156d2_ex23-3.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-FILING FEES
<SEQUENCE>5
<FILENAME>tm2410156d2_ex-filingfees.htm
<DESCRIPTION>EX-FILING FEES
<TEXT>
Document 5 - file: tm2410156d2_ex-filingfees.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>lg_apreatherapeutics-4c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 6 - file: lg_apreatherapeutics-4c.jpg

</DOCUMENT>
</SEC-DOCUMENT>