<SEC-DOCUMENT>0001104659-23-116308-index.html : 20231109
<SEC-HEADER>0001104659-23-116308.hdr.sgml : 20231109
<ACCEPTANCE-DATETIME>20231109162051
ACCESSION NUMBER:		0001104659-23-116308
CONFORMED SUBMISSION TYPE:	S-8
PUBLIC DOCUMENT COUNT:		5
FILED AS OF DATE:		20231109
DATE AS OF CHANGE:		20231109
EFFECTIVENESS DATE:		20231109

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Aprea Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001781983
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-8
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-275440
		FILM NUMBER:		231392821

	BUSINESS ADDRESS:	
		STREET 1:		3805 OLD EASTON ROAD
		CITY:			DOYLESTOWN
		STATE:			PA
		ZIP:			18902
		BUSINESS PHONE:		267-370-5219

	MAIL ADDRESS:	
		STREET 1:		3805 OLD EASTON ROAD
		CITY:			DOYLESTOWN
		STATE:			PA
		ZIP:			18902
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-8
<SEQUENCE>1
<FILENAME>tm2329846d1_s8.htm
<DESCRIPTION>FORM S-8
<TEXT>
Document 1 - file: tm2329846d1_s8.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>2
<FILENAME>tm2329846d1_ex5-1.htm
<DESCRIPTION>EXHIBIT 5.1
<TEXT>
Document 2 - file: tm2329846d1_ex5-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>3
<FILENAME>tm2329846d1_ex23-1.htm
<DESCRIPTION>EXHIBIT 23.1
<TEXT>
Document 3 - file: tm2329846d1_ex23-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-FILING FEES
<SEQUENCE>4
<FILENAME>tm2329846d1_ex-filingfees.htm
<DESCRIPTION>EX-FILING FEES
<TEXT>
Document 4 - file: tm2329846d1_ex-filingfees.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>tm2329846d1_ex5-1img002.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 5 - file: tm2329846d1_ex5-1img002.jpg

</DOCUMENT>
</SEC-DOCUMENT>