X0306 4 2019-06-28 0 0001339970 aTYR PHARMA INC LIFE 0001781292 Lucas Svetlana 3545 JOHN HOPKINS COURT SUITE 250 SAN DIEGO CA 92121 1 0 0 0 Stock Option (right to buy) 5.1296 2019-06-28 4 A 0 2285 0.00 A 2029-06-28 Common Stock 2285 2285 D The shares subject to this option shall vest and become exercisable in 36 equal monthly installments beginning July 28, 2019, such that this option will be fully exercisable on June 28, 2022, subject to the recipient's continued service on the Issuer's Board of Directors. The shares of Common Stock reported herein give effect to the 1-for-14 reverse stock split which became effective in accordance with the terms of the Certificate of Amendment to the Company's Restated Certificate of Incorporation filed with the Secretary of State of Delaware on June 28, 2019. Jill M. Broadfoot, Attorney-In-Fact 2019-07-02