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Stock-based Compensation (Tables)
 9 Months Ended
Sep. 30, 2024
Share-Based Payment Arrangement [Abstract]  
Schedule of Options Activity
The following table sets forth the summary of options activity, under the 2018 Plan and the 2021 Plans, for the nine months ended September 30, 2024:
(in thousands, except share-based data)Total OptionsWeighted- Average Exercise Price Per ShareWeighted- Average Remaining Contractual Term (In Years)Aggregate Intrinsic Value
Outstanding as of December 31, 202323,912 $68.39 
Forfeitures(4,502)11.96 
Outstanding as of September 30, 202419,410 $81.48 6.6$— 
Exercisable as of September 30, 202417,478 $76.44 6.5$— 
Vested and expected to vest as of September 30, 202419,410 $81.48 6.6$— 
Schedule of Restricted Stock Unit and Restricted Stock Award Activity
The following table sets forth the summary of RSU and RSA activity, under the Initial Plan, the 2018 Plan, the 2021 Plan, and the 2022 Plan, for the nine months ended September 30, 2024. RSAs were an immaterial portion of activity for the period:
SharesWeighted Average Grant Date Fair Value (i.e. Share Price)
Outstanding as of December 31, 2023219,720 $86.78
Vested(36,570)67.15 
Forfeited(73,718)47.72 
Outstanding as of September 30, 2024109,432 $119.66 
Schedule of Stock-Based Compensation Expense
The following table sets forth the stock-based compensation under the Initial Plan, the 2018 Plan, the 2021 Plan, and the 2022 Plan by expense type:
Three Months Ended
September 30,		Nine Months Ended
September 30,
(in thousands)2024202320242023
Research and development expenses$275 $472 $499 $1,629 
Selling, general and administrative expenses1,432 1,684 4,386 4,824 
Total$1,707 $2,156 $4,885 $6,453 
The following table sets forth the stock-based compensation under the Initial Plan, the 2018 Plan, the 2021 Plan, and the 2022 Plan by award type:
Three Months Ended
September 30,		Nine Months Ended
September 30,
(in thousands)2024202320242023
Options$71 $81 $216 $269 
RSUs & RSAs1,636 2,068 4,669 6,167 
ESPP— 7 — 17 
Total$1,707 $2,156 $4,885 $6,453