X0306 4/A 2020-06-08 2020-06-10 0 0001755953 Akerna Corp. KERN 0001780003 Billingsley Jessica C/O AKERNA CORP. 1630 WELTON STREET, FLOOR 4 DENVER CO 80202 1 1 1 0 Chairman and CEO Common Shares 2020-06-08 4 J 0 270000 D 1065802 I Jessica Billingsley Living Trust Common Shares 2020-06-08 4 J 0 270000 A 270000 D Common Shares 2020-06-08 4 S 0 60000 10.5012 D 210000 D Common Shares 2020-06-09 4 S 0 10000 10.4415 D 200000 D Represents transfer of shares from Jessica Billingsley Living Trust to the reporting person. The reporting person is the trustee of Jessica Billingsley Living Trust and has voting and investment discretion with respect to the shares of common stock held of record by the Jessica Billingsley Living Trust, and may have or share beneficial ownership of such shares. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at price ranging from $10.00 to $11.37, inclusive. The reporting person undertakes to provide to Akerna Corp., any security holder of Akerna Corp., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at price ranging from $10.11 to $11.75, inclusive. The reporting person undertakes to provide to Akerna Corp., any security holder of Akerna Corp., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote. Exhibit 24.1 Power of Attorney /s/ John Michael Fowle Jr. as attorney-in-fact for Jessica Billingsley 2022-04-05