144 0001779990 XXXXXXXX LIVE 0001974640 Apogee Therapeutics, Inc. 001-41740 221 CRESCENT ST. BUILDING 17, SUITE 102B WALTHAM MA 02453 650-394-5230 HENDERSON MICHAEL THOMAS Officer Director COMMON THE CHARLES SCHWAB CORPORATION

3000 Schwab Way Westlake TX 76262

60000 4948200.00 75389375 05/13/2026 NASDAQ COMMON 10/02/2023 RSU VESTING PER FOLLOWING DATES: 10/02/23 thru 1/2/24 ISSUER N 60000 10/02/2023 NA N MICHAEL HENDERSON

221 Crescent St Building 17 Suite 102b Waltham MA 02453

COMMON 03/11/2026 20000 1495597.00 MICHAEL HENDERSON

221 Crescent St Building 17 Suite 102b Waltham MA 02453

COMMON 04/08/2026 20000 1651600.00 05/13/2026 08/13/2025 MICHAEL HENDERSON