The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
4D MOLECULAR THERAPEUTICS IN COM 35104E100   421 39 SH   SOLE   39 0 0
ABEONA THERAPEUTICS INC COM NEW 00289Y206   3,688,308 583,593 SH   SOLE   583,593 0 0
ACELYRIN INC COM 00445A100   3,337,975 677,074 SH   SOLE   677,074 0 0
ACHILLES THERAPEUTICS PLC SPONSORED ADS 00449L102   1,472,045 1,443,181 SH   SOLE   1,443,181 0 0
ACUMEN PHARMACEUTICALS INC COM 00509G209   660,759 266,435 SH   SOLE   266,435 0 0
AEON BIOPHARMA INC CL A 00791X100   270,876 257,977 SH   SOLE   257,977 0 0
AEROVATE THERAPEUTICS INC COM 008064107   769,046 367,965 SH   SOLE   367,965 0 0
AKERO THERAPEUTICS INC COM 00973Y108   5,706,441 198,900 SH Put SOLE   198,900 0 0
ALLAKOS INC COM 01671P100   635,352 972,675 SH   SOLE   972,675 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107   2,404,038 8,741 SH   SOLE   8,741 0 0
ALTO NEUROSCIENCE INC COM SHS 02157Q109   5,148,000 450,000 SH Put SOLE   450,000 0 0
ALTO NEUROSCIENCE INC COM SHS 02157Q109   4,930,640 431,000 SH Call SOLE   431,000 0 0
AMGEN INC COM 031162100   47,042,660 146,000 SH Call SOLE   146,000 0 0
AMGEN INC COM 031162100   4,285,394 13,300 SH   SOLE   13,300 0 0
AMYLYX PHARMACEUTICALS INC COM 03237H101   889,546 274,551 SH   SOLE   274,551 0 0
ANAPTYSBIO INC COM 032724106   13,544,050 404,300 SH Put SOLE   404,300 0 0
ANAPTYSBIO INC COM 032724106   11,725,000 350,000 SH Call SOLE   350,000 0 0
ANEBULO PHARMACEUTICALS INC COM 034569103   304,675 157,862 SH   SOLE   157,862 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106   5,768,000 200,000 SH Put SOLE   200,000 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106   4,326,000 150,000 SH Call SOLE   150,000 0 0
APOGEE THERAPEUTICS INC COM 03770N101   293,700 5,000 SH Call SOLE   5,000 0 0
ARCUS BIOSCIENCES INC COM 03969F109   1,738,473 113,700 SH Call SOLE   113,700 0 0
ARCUS BIOSCIENCES INC COM 03969F109   11,375,760 744,000 SH   SOLE   744,000 0 0
AVALO THERAPEUTICS INC COM NEW 05338F306   9,218,411 970,359 SH   SOLE   970,359 0 0
BEIGENE LTD SPONSORED ADR 07725L102   6,690,398 29,800 SH Call SOLE   29,800 0 0
BEIGENE LTD SPONSORED ADR 07725L102   1,641,345 88,167 SH   SOLE   88,167 0 0
BIOHAVEN LTD COM G1110E107   16,270,232 325,600 SH Put SOLE   325,600 0 0
BIOMEA FUSION INC COM 09077A106   535,300 53,000 SH Put SOLE   53,000 0 0
BIOMX INC COM NEW 09090D301   910,860 893,000 SH   SOLE   893,000 0 0
BLACK DIAMOND THERAPEUTICS I COM 09203E105   4,132,500 950,000 SH Put SOLE   950,000 0 0
BLACK DIAMOND THERAPEUTICS I COM 09203E105   3,045,000 700,000 SH Call SOLE   700,000 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109   7,862,501 85,000 SH   SOLE   85,000 0 0
BRIDGEBIO PHARMA INC COM 10806X102   7,271,706 285,613 SH   SOLE   285,613 0 0
CAPRICOR THERAPEUTICS INC COM NEW 14070B309   4,563,000 300,000 SH Put SOLE   300,000 0 0
CAPRICOR THERAPEUTICS INC COM NEW 14070B309   4,563,000 300,000 SH Call SOLE   300,000 0 0
CAPRICOR THERAPEUTICS INC COM NEW 14070B309   4,563,000 300,000 SH   SOLE   300,000 0 0
CARTESIAN THERAPEUTICS INC COM NEW 816212302   841,352 52,193 SH   SOLE   52,193 0 0
CATALYST PHARMACEUTICALS INC COM 14888U101   8,306,858 417,850 SH   SOLE   417,850 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202   10,383,945 305,500 SH Put SOLE   305,500 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202   10,383,945 305,500 SH Call SOLE   305,500 0 0
CERVOMED INC COM 15713L109   2,954,237 202,345 SH   SOLE   202,345 0 0
CHEMOMAB THERAPEUTICS LTD SPONSORED ADS 16385C104   335,025 213,392 SH   SOLE   213,392 0 0
COMPASS PATHWAYS PLC SPONSORED ADS 20451W101   1,278,320 202,908 SH   SOLE   202,908 0 0
CORBUS PHARMACEUTICALS HLDGS COM NEW 21833P301   4,808,853 233,100 SH Put SOLE   233,100 0 0
CORBUS PHARMACEUTICALS HLDGS COM NEW 21833P301   2,223,914 107,800 SH Call SOLE   107,800 0 0
CORBUS PHARMACEUTICALS HLDGS COM NEW 21833P301   5,873,670 284,715 SH   SOLE   284,715 0 0
CORVUS PHARMACEUTICALS INC COM 221015100   1,152,624 218,300 SH Call SOLE   218,300 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107   21,815,255 426,913 SH   SOLE   426,913 0 0
CYBIN INC COM NEW 23256X407   3,264,364 367,195 SH   SOLE   367,195 0 0
CYTOKINETICS INC COM NEW 23282W605   2,761,440 52,300 SH Call SOLE   52,300 0 0
CYTOKINETICS INC COM NEW 23282W605   8,983,761 170,147 SH   SOLE   170,147 0 0
CYTOMX THERAPEUTICS INC COM 23284F105   10,529 8,924 SH   SOLE   8,924 0 0
DELCATH SYS INC COM NEW 24661P807   906,340 100,370 SH   SOLE   100,370 0 0
DYNE THERAPEUTICS INC COM 26818M108   4,777,360 133,000 SH Put SOLE   133,000 0 0
ELEVATION ONCOLOGY INC COM 28623U101   413,984 690,089 SH   SOLE   690,089 0 0
ELIEM THERAPEUTICS INC COM 28658R106   891,258 175,100 SH   SOLE   175,100 0 0
ENLIVEN THERAPEUTICS INC COM 29337E102   12,758,915 499,566 SH   SOLE   499,566 0 0
EVOLUS INC COM 30052C107   4,184,120 258,279 SH   SOLE   258,279 0 0
FULCRUM THERAPEUTICS INC COM 359616109   81,396 22,800 SH Put SOLE   22,800 0 0
FULCRUM THERAPEUTICS INC COM 359616109   1,509,396 422,800 SH Call SOLE   422,800 0 0
FULCRUM THERAPEUTICS INC COM 359616109   267,750 75,000 SH   SOLE   75,000 0 0
GALECTIN THERAPEUTICS INC COM NEW 363225202   1,375,000 500,000 SH Put SOLE   500,000 0 0
GALECTIN THERAPEUTICS INC COM NEW 363225202   1,375,000 500,000 SH Call SOLE   500,000 0 0
HOOKIPA PHARMA INC COM NEW 43906K209   228,227 53,076 SH   SOLE   53,076 0 0
IBIO INC CON NEW 451033708   1,332,000 600,000 SH   SOLE   600,000 0 0
IMMATICS N.V SHS N44445109   563,825 49,415 SH   SOLE   49,415 0 0
IMMUNIC INC COM 4525EP101   814,268 493,496 SH   SOLE   493,496 0 0
IMMUNOVANT INC COM 45258J102   14,255,000 500,000 SH Call SOLE   500,000 0 0
INFLARX NV COM N44821101   1,078,630 704,987 SH   SOLE   704,987 0 0
INHIBRX BIOSCIENCES INC COM 45720N103   659,646 42,123 SH   SOLE   42,123 0 0
INSMED INC COM PAR $.01 457669307   11,302,955 154,835 SH   SOLE   154,835 0 0
ITEOS THERAPEUTICS INC COM 46565G104   802,241 78,574 SH   SOLE   78,574 0 0
JANUX THERAPEUTICS INC COM 47103J105   16,591,036 365,200 SH Put SOLE   365,200 0 0
JASPER THERAPEUTICS INC COM NEW 471871202   1,037,842 55,175 SH   SOLE   55,175 0 0
KARYOPHARM THERAPEUTICS INC COM 48576U106   339,764 409,355 SH   SOLE   409,355 0 0
KEZAR LIFE SCIENCES INC COM 49372L100   826,544 1,068,992 SH   SOLE   1,068,992 0 0
KODIAK SCIENCES INC COM 50015M109   1,243,890 476,586 SH   SOLE   476,586 0 0
LARIMAR THERAPEUTICS INC COM 517125100   383,358 58,528 SH   SOLE   58,528 0 0
LENZ THERAPEUTICS INC COM 52635N103   4,855,139 204,513 SH   SOLE   204,513 0 0
LEXEO THERAPEUTICS INC COM 52886X107   2,325,233 257,216 SH   SOLE   257,216 0 0
LYELL IMMUNOPHARMA INC COM 55083R104   725,971 526,066 SH   SOLE   526,066 0 0
LYRA THERAPEUTICS INC COM 55234L105   271,606 1,056,829 SH   SOLE   1,056,829 0 0
MACROGENICS INC COM 556099109   263,460 80,079 SH   SOLE   80,079 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105   4,987,170 23,500 SH Put SOLE   23,500 0 0
MARINUS PHARMACEUTICALS INC COM NEW 56854Q200   1,242,831 706,154 SH   SOLE   706,154 0 0
MILESTONE PHARMACEUTICALS IN COM 59935V107   708,349 466,019 SH   SOLE   466,019 0 0
MIND MEDICINE MINDMED INC COM NEW 60255C885   355,516 62,481 SH   SOLE   62,481 0 0
MINERALYS THERAPEUTICS INC COM 603170101   2,179,800 180,000 SH   SOLE   180,000 0 0
MONTE ROSA THERAPEUTICS INC COM 61225M102   1,651,443 311,593 SH   SOLE   311,593 0 0
NEKTAR THERAPEUTICS COM 640268108   1,706,126 1,312,405 SH   SOLE   1,312,405 0 0
NEUMORA THERAPEUTICS INC. COM 640979100   5,284,000 400,000 SH Put SOLE   400,000 0 0
NEUMORA THERAPEUTICS INC. COM 640979100   5,284,000 400,000 SH Call SOLE   400,000 0 0
NEWAMSTERDAM PHARMA COMPANY ORDINARY SHARES N62509109   483,060 29,100 SH Call SOLE   29,100 0 0
NURIX THERAPEUTICS INC COM 67080M103   5,842,200 260,000 SH   SOLE   260,000 0 0
NUVALENT INC COM 670703107   5,343,947 52,238 SH   SOLE   52,238 0 0
NUVATION BIO INC COM CL A 67080N101   190,716 83,282 SH   SOLE   83,282 0 0
NYXOAH S A SHS B6S7WD106   484,175 50,699 SH   SOLE   50,699 0 0
OLEMA PHARMACEUTICALS INC COM 68062P106   1,098,479 92,000 SH   SOLE   92,000 0 0
PERSPECTIVE THERAPEUTICS INC COM NEW 46489V302   1,029,285 77,100 SH Put SOLE   77,100 0 0
PROQR THRAPEUTICS N V SHS EURO N71542109   880,121 483,583 SH   SOLE   483,583 0 0
PROTARA THERAPEUTICS INC COM STK 74365U107   284,953 155,712 SH   SOLE   155,712 0 0
PROTHENA CORP PLC SHS G72800108   197,414 11,800 SH Put SOLE   11,800 0 0
PROTHENA CORP PLC SHS G72800108   197,414 11,800 SH Call SOLE   11,800 0 0
PYXIS ONCOLOGY INC COMMON STOCK 747324101   1,316,062 358,600 SH Call SOLE   358,600 0 0
PYXIS ONCOLOGY INC COMMON STOCK 747324101   3,513,688 957,408 SH   SOLE   957,408 0 0
RAPT THERAPEUTICS INC COM 75382E109   310,796 154,625 SH   SOLE   154,625 0 0
RELAY THERAPEUTICS INC COM 75943R102   4,908,918 693,350 SH   SOLE   693,350 0 0
RELMADA THERAPEUTICS INC COM 75955J402   130,795 40,369 SH   SOLE   40,369 0 0
RENEO PHARMACEUTICALS INC COM 75974E103   1,743,635 1,025,668 SH   SOLE   1,025,668 0 0
REZOLUTE INC COM NEW 76200L309   4,303,066 887,230 SH   SOLE   887,230 0 0
ROCKET PHARMACEUTICALS INC COM 77313F106   3,640,363 197,096 SH   SOLE   197,096 0 0
ROIVANT SCIENCES LTD SHS G76279101   1,161,028 100,609 SH   SOLE   100,609 0 0
SAGIMET BIOSCIENCES INC COM SER A 786700104   1,073,555 387,565 SH   SOLE   387,565 0 0
SANA BIOTECHNOLOGY INC COM 799566104   2,704,000 650,000 SH Put SOLE   650,000 0 0
SANA BIOTECHNOLOGY INC COM 799566104   2,704,000 650,000 SH Call SOLE   650,000 0 0
SAREPTA THERAPEUTICS INC COM 803607100   6,766,041 54,176 SH   SOLE   54,176 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103   1,618,821 202,100 SH Put SOLE   202,100 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103   1,618,821 202,100 SH Call SOLE   202,100 0 0
SENSEI BIOTHERAPEUTICS INC COM 81728A108   388,700 650,000 SH   SOLE   650,000 0 0
SILENCE THERAPEUTICS PLC ADS 82686Q101   3,374,286 587,343 SH   SOLE   587,343 0 0
SOLENO THERAPEUTICS INC COM 834203309   5,553,900 110,000 SH Call SOLE   110,000 0 0
SOLENO THERAPEUTICS INC COM 834203309   11,180,355 221,437 SH   SOLE   221,437 0 0
SOLID BIOSCIENCES INC COM NEW 83422E204   2,091,000 300,000 SH Call SOLE   300,000 0 0
SPDR SER TR S&P BIOTECH 78464A870   49,400,000 500,000 SH Put SOLE   500,000 0 0
SPRINGWORKS THERAPEUTICS INC COM 85205L107   1,403,352 43,800 SH Call SOLE   43,800 0 0
SPYRE THERAPEUTICS INC COM NEW 00773J202   8,889,085 302,247 SH   SOLE   302,247 0 0
STOKE THERAPEUTICS INC COM 86150R107   83,768 6,816 SH   SOLE   6,816 0 0
STRUCTURE THERAPEUTICS INC SPONSORED ADS 86366E106   5,056,129 115,200 SH   SOLE   115,200 0 0
SYNLOGIC INC COM NEW 87166L209   30,468 20,448 SH   SOLE   20,448 0 0
TARSUS PHARMACEUTICALS INC COM 87650L103   33,885,812 1,030,277 SH   SOLE   1,030,277 0 0
TECTONIC THERAPEUTIC INC COM 878972108   8,094,495 267,145 SH   SOLE   267,145 0 0
TEMPEST THERAPEUTICS INC COM 87978U108   147,840 105,600 SH   SOLE   105,600 0 0
TERNS PHARMACEUTICALS INC COM 880881107   2,572,865 308,497 SH   SOLE   308,497 0 0
TOURMALINE BIO INC COM 89157D105   2,789,099 108,483 SH   SOLE   108,483 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108   9,943,450 179,000 SH   SOLE   179,000 0 0
VENTYX BIOSCIENCES INC COM 92332V107   419,970 192,647 SH   SOLE   192,647 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100   46,508,000 100,000 SH Put SOLE   100,000 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100   46,508,000 100,000 SH Call SOLE   100,000 0 0
VERU INC COM 92536C103   727,767 946,382 SH   SOLE   946,382 0 0
VERVE THERAPEUTICS INC COM 92539P101   822,800 170,000 SH   SOLE   170,000 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104   4,550,000 200,000 SH Call SOLE   200,000 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104   11,374,478 499,977 SH   SOLE   499,977 0 0
VOYAGER THERAPEUTICS INC COM 92915B106   326,763 55,857 SH   SOLE   55,857 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105   4,462,973 544,265 SH   SOLE   544,265 0 0
XENON PHARMACEUTICALS INC COM 98420N105   4,219,953 107,187 SH   SOLE   107,187 0 0