0001420506-22-000935.txt : 20220513 0001420506-22-000935.hdr.sgml : 20220513 20220513160504 ACCESSION NUMBER: 0001420506-22-000935 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20220331 FILED AS OF DATE: 20220513 DATE AS OF CHANGE: 20220513 EFFECTIVENESS DATE: 20220513 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Ikarian Capital, LLC CENTRAL INDEX KEY: 0001778253 IRS NUMBER: 473466768 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-19721 FILM NUMBER: 22922611 BUSINESS ADDRESS: STREET 1: 100 CRESCENT COURT STREET 2: SUITE 1620 CITY: DALLAS STATE: TX ZIP: 75201 BUSINESS PHONE: 214-364-2883 MAIL ADDRESS: STREET 1: 100 CRESCENT COURT STREET 2: SUITE 1620 CITY: DALLAS STATE: TX ZIP: 75201 13F-HR 1 primary_doc.xml 13F-HR LIVE false true false 0001778253 XXXXXXXX 03-31-2022 03-31-2022 false Ikarian Capital, LLC

100 CRESCENT COURT SUITE 1620 DALLAS TX 75201

13F HOLDINGS REPORT 028-19721 N Troy Wuertz 214-276-0670 Troy Wuertz, CHIEF COMPLIANCE OFFICER DALLAS TX 05-13-2022 0 196 760463 false INFORMATION TABLE 2 Form13F_InfoTable.xml INFORMATION TABLE FOR IKARIAN CAPITAL, LLC 2SEVENTY BIO INC COMMON STOCK 901384107 1 99 SH SOLE 99 0 0 AADI BIOSCIENCE INC COM 00032Q104 3536 208368 SH SOLE 208368 0 0 ACADIA PHARMACEUTICALS INC COM 004225108 46 1882 SH SOLE 1882 0 0 ACLARIS THERAPEUTICS INC COM 00461U105 208 12124 SH SOLE 12124 0 0 ADICET BIO INC COM 007002108 1241 62100 SH Call SOLE 62100 0 0 ADICET BIO INC COM 007002108 10132 507348 SH SOLE 507348 0 0 AGENUS INC COM NEW 00847G705 267 108933 SH SOLE 108933 0 0 AILERON THERAPEUTICS INC COM 00887A105 1487 2902086 SH SOLE 2902086 0 0 AKEBIA THERAPEUTICS INC COM 00972D105 860 1200000 SH Put SOLE 1200000 0 0 AKEBIA THERAPEUTICS INC COM 00972D105 575 800000 SH Call SOLE 800000 0 0 ALDEYRA THERAPEUTICS INC COM 01438T106 1667 375000 SH SOLE 375000 0 0 ALNYLAM PHARMACEUTICALS INC COM 02043Q107 201 1237 SH SOLE 1237 0 0 ALNYLAM PHARMACEUTICALS INC COM 02043Q107 19235 117800 SH Put SOLE 117800 0 0 ALNYLAM PHARMACEUTICALS INC COM 02043Q107 22077 135200 SH Call SOLE 135200 0 0 ALTAMIRA THERAPEUTICS LTD SHS G0360L100 351 320010 SH SOLE 320010 0 0 AMGEN INC COM 031162100 4837 20000 SH SOLE 20000 0 0 AMGEN INC COM 031162100 24182 100000 SH Call SOLE 100000 0 0 AMRYT PHARMA PLC SPONSORED ADS 03217L106 70 37248 SH SOLE 37248 0 0 AMYLYX PHARMACEUTICALS INC COM 03237H101 5097 396654 SH SOLE 396654 0 0 AMYLYX PHARMACEUTICALS INC COM 03237H101 3213 250000 SH Call SOLE 250000 0 0 ANEBULO PHARMACEUTICALS INC COM 034569103 1225 181199 SH SOLE 181199 0 0 APELLIS PHARMACEUTICALS INC COM 03753U106 8896 175100 SH Call SOLE 175100 0 0 APPLIED GENETIC TECHNOLOGIES COM 03820J100 440 412293 SH SOLE 412293 0 0 APTOSE BIOSCIENCES INC COM NEW 03835T200 147 106952 SH SOLE 106952 0 0 ARCUS BIOSCIENCES INC COM 03969F109 4734 150000 SH Call SOLE 150000 0 0 ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 1028 8763 SH 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6283 913327 SH SOLE 913327 0 0 BICYCLE THERAPEUTICS PLC SPONSORED ADS 088786108 11617 264700 SH Call SOLE 264700 0 0 BICYCLE THERAPEUTICS PLC SPONSORED ADS 088786108 4677 106600 SH Put SOLE 106600 0 0 BICYCLE THERAPEUTICS PLC SPONSORED ADS 088786108 21009 478784 SH SOLE 478784 0 0 BIOGEN INC COM 09062X103 23629 112200 SH Call SOLE 112200 0 0 BIOGEN INC COM 09062X103 237 1122 SH SOLE 1122 0 0 BIOHAVEN PHARMACTL HLDG CO L COM G11196105 7114 60000 SH SOLE 60000 0 0 BIOMARIN PHARMACEUTICAL INC COM 09061G101 3856 50000 SH SOLE 50000 0 0 BIOMARIN PHARMACEUTICAL INC COM 09061G101 24192 313800 SH Call SOLE 313800 0 0 BIOXCEL THERAPEUTICS INC COM 09075P105 113 5428 SH SOLE 5428 0 0 BLACK DIAMOND THERAPEUTICS I COM 09203E105 441 159390 SH SOLE 159390 0 0 BLUEBIRD BIO INC COM 09609G100 1 306 SH SOLE 306 0 0 BLUEPRINT MEDICINES CORP COM 09627Y109 4088 64000 SH Call SOLE 64000 0 0 BRAINSTORM CELL THERAPEUTICS COM NEW 10501E201 1022 304161 SH SOLE 304161 0 0 BRIGHT MINDS BIOSCIENCES INC COM 10919W108 161 105958 SH SOLE 105958 0 0 CABALETTA BIO INC COM 12674W109 2070 1020070 SH SOLE 1020070 0 0 CABALETTA BIO INC COM 12674W109 912 449000 SH Call SOLE 449000 0 0 CASI PHARMACEUTICALS INC COM 14757U109 1067 1320155 SH SOLE 1320155 0 0 CATALYST BIOSCIENCES INC COM NEW 14888D208 314 476625 SH SOLE 476625 0 0 CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 18323 537958 SH SOLE 537958 0 0 CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 11718 344100 SH Call SOLE 344100 0 0 CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 20282 595500 SH Put SOLE 595500 0 0 CHEMOMAB THERAPEUTICS LTD SPONSORED ADS 16385C104 1292 268104 SH SOLE 268104 0 0 CHIMERIX INC COM 16934W106 3852 841203 SH SOLE 841203 0 0 CLENE INC COMMON STOCK 185634102 2026 514283 SH SOLE 514283 0 0 CLOVIS ONCOLOGY INC COM 189464100 1561 772339 SH SOLE 772339 0 0 CODIAK BIOSCIENCES INC COM 192010106 328 52177 SH SOLE 52177 0 0 COMPASS THERAPEUTICS INC COM 20454B104 100 74171 SH SOLE 74171 0 0 CONNECT BIOPHARMA HLDGS LTD ADS 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COM NEW 45257F200 399 77650 SH SOLE 77650 0 0 INFLARX NV COM N44821101 639 349468 SH SOLE 349468 0 0 INHIBRX INC COM 45720L107 1911 85800 SH Call SOLE 85800 0 0 INHIBRX INC COM 45720L107 3516 157842 SH SOLE 157842 0 0 INTELLIA THERAPEUTICS INC COM 45826J105 3445 47408 SH SOLE 47408 0 0 INTERCEPT PHARMACEUTICALS IN COM 45845P108 572 35149 SH SOLE 35149 0 0 INVENTIVA SA ADS 46124U107 178 15579 SH SOLE 15579 0 0 IVERIC BIO INC COM 46583P102 825 49099 SH SOLE 49099 0 0 KALVISTA PHARMACEUTICALS INC COM 483497103 586 39730 SH SOLE 39730 0 0 KARUNA THERAPEUTICS INC COM 48576A100 6340 50000 SH SOLE 50000 0 0 KARYOPHARM THERAPEUTICS INC COM 48576U106 6 830 SH SOLE 830 0 0 KEZAR LIFE SCIENCES INC COM 49372L100 18001 1083116 SH SOLE 1083116 0 0 KEZAR LIFE SCIENCES INC COM 49372L100 4666 280800 SH Call SOLE 280800 0 0 KINNATE BIOPHARMA INC COM 49705R105 22 1990 SH SOLE 1990 0 0 KODIAK SCIENCES INC COM 50015M109 565 73100 SH Put SOLE 73100 0 0 KODIAK SCIENCES INC COM 50015M109 199 25700 SH Call SOLE 25700 0 0 KODIAK SCIENCES INC COM 50015M109 526 68100 SH SOLE 68100 0 0 KYMERA THERAPEUTICS INC COM 501575104 2117 50000 SH SOLE 50000 0 0 LARIMAR THERAPEUTICS INC COM 517125100 209 51606 SH SOLE 51606 0 0 LIQUIDIA CORPORATION COM NEW 53635D202 1751 243904 SH SOLE 243904 0 0 LYRA THERAPEUTICS INC COM 55234L105 1698 422338 SH SOLE 422338 0 0 MACROGENICS INC COM 556099109 1446 164119 SH SOLE 164119 0 0 MAXCYTE INC COM 57777K106 964 137958 SH SOLE 137958 0 0 MEREO BIOPHARMA GROUP PLC ADS 589492107 318 915856 SH SOLE 915856 0 0 MERUS N V COM N5749R100 1420 53703 SH SOLE 53703 0 0 MILESTONE PHARMACEUTICALS IN COM 59935V107 12383 1928752 SH SOLE 1928752 0 0 MIND MEDICINE MINDMED INC COM SUB VTG 60255C109 118 105958 SH SOLE 105958 0 0 MUSTANG BIO INC COM 62818Q104 551 546824 SH SOLE 546824 0 0 MYMD PHARMACEUTICALS INC COM 62856X102 612 131389 SH SOLE 131389 0 0 NEKTAR THERAPEUTICS COM 640268108 722 133900 SH Call SOLE 133900 0 0 NEUROCRINE BIOSCIENCES INC COM 64125C109 40277 429600 SH 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0 0 PFIZER INC COM 717081103 4142 80000 SH SOLE 80000 0 0 PHATHOM PHARMACEUTICALS INC COM 71722W107 1069 78550 SH SOLE 78550 0 0 PLIANT THERAPEUTICS INC COM 729139105 636 90805 SH SOLE 90805 0 0 PMV PHARMACEUTICALS INC COM 69353Y103 2082 100000 SH Call SOLE 100000 0 0 PMV PHARMACEUTICALS INC COM 69353Y103 2082 100000 SH Put SOLE 100000 0 0 PROTAGONIST THERAPEUTICS INC COM 74366E102 3806 160700 SH Call SOLE 160700 0 0 PROTARA THERAPEUTICS INC COM STK 74365U107 1515 296426 SH SOLE 296426 0 0 PUMA BIOTECHNOLOGY INC COM 74587V107 144 49843 SH SOLE 49843 0 0 QUANTUM SI INC COM CL A 74765K105 736 157363 SH SOLE 157363 0 0 REATA PHARMACEUTICALS INC CL A 75615P103 502 15300 SH Call SOLE 15300 0 0 REATA PHARMACEUTICALS INC CL A 75615P103 2846 86905 SH SOLE 86905 0 0 REATA PHARMACEUTICALS INC CL A 75615P103 21281 649600 SH Put SOLE 649600 0 0 REGULUS THERAPEUTICS INC COM NEW 75915K200 384 1289130 SH SOLE 1289130 0 0 RELMADA THERAPEUTICS INC COM 75955J402 588 21801 SH SOLE 21801 0 0 RENEO 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