X0206 3 2019-05-22 0 0001761612 BICYCLE THERAPEUTICS Ltd BCYC 0001777021 Winter Gregory Paul C/O BICYCLE THERAPEUTICS PLC B900, BABRAHAM RESEARCH CAMPUS CAMBRIDGE X0 CB22 3AT UNITED KINGDOM 1 0 0 0 Ordinary Shares 49607 D Series A Preferred Shares Ordinary Shares 42870 D Series A Preferred Shares Warrant 2027-05-26 Series A Preferred Shares 71450 D Each Series A Preferred Share shall automatically convert into Ordinary Shares on a one for 1.429 basis immediately prior to the closing of the Issuer's initial public offering and have no expiration date. Share numbers give effect to the bonus shares issued to each holder of ordinary shares on the basis of 1.429 bonus shares for each ordinary share in issue, effective on May 13, 2019, which will be effective for the ordinary shares upon their conversion to ordinary shares upon the closing of the Issuer's initial public offering. The number of shares reflects the conversion of the Series B1 Preferred Shares and the Series B2 Preferred Shares to Ordinary Shares set out in footnote (1). The Warrants to purchase Series A Preferred Shares have an exercise price of a nominal value per share. The Warrants are immediately exercisable and expire on May 26, 2027. Exhibit 24 - Power of Attorney /s/ Lee Kalowski, as Attorney-in-Fact 2019-05-22