144 0001803150 XXXXXXXX LIVE 0001776985 BioNTech SE 001-39081 AN DER GOLDGRUBE 12 MAINZ 2M 55131 0049613190840 Medine GmbH Officer 10% Stockholder American Depositary Shares representing ordinary shares, no par value per share Berenberg Capital Markets LLC

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858209 80379854.94 252884261 05/13/2026 Nasdaq Global Select Ordinary Shares, no par value per share 11/21/2022 Stock Option Exercise BioNTech SE N 856186 11/21/2022 Stock Option Exercise Ordinary Shares, no par value per share 08/09/2024 Stock Option Exercise BioNTech SE N 2023 08/09/2024 Stock Option Exercise Y The filing of this Form 144 shall not be construed as an admission that the undersigned is an affiliate of the issuer. 05/12/2026 /s/ Ugur Sahin