X0407 4 2023-05-31 0 0001757898 STERIS plc STE 0001776271 Majors Cary L C/O 70 SIR JOHN ROGERSON'S QUAY DUBLIN L2 2 IRELAND 0 1 0 0 SVP and President, Healthcare 0 Ordinary Shares 2023-05-31 4 F 0 649 199.97 D 10696 D Ordinary Shares 2023-05-31 4 A 0 2697 0.00 A 13393 D Employee Stock Option (right to buy) 219.97 2023-05-31 4 A 0 15148 0.00 A 2033-05-31 Ordinary Shares 15148 15148 D 649 shares were withheld from the 2,224 restricted shares that vested on May 31, 2023. These 649 shares represent the value of the taxes required to be withheld pursuant to applicable employment or tax laws, as determined by the Issuer. These 2,224 ordinary shares were awarded to Mr. Majors on May 31, 2019. These vested shares were valued at the NYSE closing market price on May 31, 2023. As of May 31, 2023, 9,860 of these ordinary shares are restricted. The restrictions on these ordinary shares lapse as follows: 2,367 on June 3, 2024; 1,964 on June 2, 2025; 692 on October 1, 2025; 2,697 on June 1, 2026 and 2,140 on June 2, 2026. This option becomes exercisable as follows: 3,787 on May 31, 2024; 3,787 on June 2, 2025; 3,787 on June 1, 2026 and 3,787 on June 1, 2027. /s/ Ronald E. Snyder, Authorized Representative under Power of Attorney 2023-06-02