X0306 4 2019-08-07 0 0001757898 STERIS plc STE 0001776271 Majors Cary L C/O 70 SIR JOHN ROGERSON'S QUAY DUBLIN L2 2 IRELAND 0 1 0 0 VP, N America Com Operations Ordinary Shares 2019-08-07 4 M 0 2250 66.15 A 21445 D Ordinary Shares 2019-08-07 4 S 0 2250 152.68 D 19195 D Ordinary Shares 2019-08-07 4 M 0 3000 69.72 A 22195 D Ordinary Shares 2019-08-07 4 S 0 3000 152.66 D 19195 D Employee Stock Option (right to buy) 66.15 2019-08-07 4 M 0 2250 0.00 D 2025-05-28 Ordinary Shares 2250 0 D Employee Stock Option (right to buy) 69.72 2019-08-07 4 M 0 3000 0.00 D 2026-06-01 Ordinary Shares 3000 3000 D Price reflects a weighted average sale price for multiple transactions ranging from $152.65 to $152.73 per share, inclusive. The Reporting Person undertakes to provide, upon request by the SEC Staff, the Issuer or a security holder of the Issuer, full information regarding the number of shares sold at each separate price. Price reflects a weighted average sale price for multiple transactions ranging from $152.65 to $152.67 per share, inclusive. The Reporting Person undertakes to provide, upon request by the SEC Staff, the Issuer or a security holder of the Issuer, full information regarding the number of shares sold at each separate price. 16,744 of these ordinary shares are restricted. The restrictions on these ordinary shares lapse as follows: 3,000 on October 1, 2019; 2,500 on June 1, 2020; 6,500 on May 31, 2021; 2,520 on May 31, 2022; and 2,224 on May 31, 2023. This option to purchase 2,250 STERIS ordinary shares, which is fully vested, was received in conjunction with the Redomiciliation of the entity organized under the laws of the U.K. and formerly named STERIS plc ("Old STERIS") in exchange for an option to purchase 2,250 Old STERIS ordinary shares for $66.15 per share, subject to the same terms and conditions as the original Old STERIS stock option, except as otherwise required by law. This option to purchase 6,000 STERIS ordinary shares, of which the 3,000 ordinary shares being exercised have fully vested, was received in conjunction with the Redomiciliation of the entity organized under the laws of the U.K. and formerly named STERIS plc ("Old STERIS") in exchange for an option to purchase 6,000 Old STERIS ordinary shares for $69.72 per share, subject to the same terms and conditions as the original Old STERIS stock option, except as otherwise required by law. /s/ Ronald E. Snyder, Authorized Representative under Power of Attorney 2019-08-09