X0306 4 2022-05-25 0 0001463361 Unity Biotechnology, Inc. UBX 0001775910 Samar Michael P. C/O UNITY BIOTECHNOLOGY, INC. 285 EAST GRAND AVENUE SOUTH SAN FRANCISCO CA 94080 1 0 0 0 Stock Option (Right to Buy) 0.76 2022-05-25 4 A 0 50000 0.00 A 2032-05-24 Common Stock 50000 50000 D Shares subject to the stock option vest and become exercisable in successive, equal monthly installments over a 36-month period commencing on May 25, 2022 (the "Vesting Commencement Date"), so that 100% of the shares become fully vested and exercisable on the third anniversary of the Vesting Commencement Date, subject to Reporting Person's continued service relationship with the Issuer on each such vesting date. /s/ Alexander Hieu Nguyen, Attorney-in-Fact for Michael P. Samar 2022-05-26