X0306 4/A 2021-06-23 2021-06-25 0 0001652130 Intellia Therapeutics, Inc. NTLA 0001773532 Keresty Georgia C/O INTELLIA THERAPEUTICS, INC. 40 ERIE STREET; SUITE 130 CAMBRIDGE MA 02139 1 0 0 0 Common Stock 2021-06-23 4 A 0 1569 0.00 A 6524 D Stock Option (right to buy) 83.59 2021-06-23 4 A 0 2534 0.00 A 2031-06-22 Common Stock 2534 2534 D Based on a grant of restricted stock units representing a contingent right to receive one share of Intellia common stock for each restricted stock unit. This option was granted on June 23, 2021 with respect to 2,534 shares of Common Stock and vests in full on the earlier to occur of (a) the first anniversary of the grant date or (b) the date of the next annual meeting of stockholders following the date of grant. The Form 4/A amends and restates the original Form 4 filed on June 25, 2021 to correct the number of shares of common stock and stock options granted to the reporting person. /s/James Basta, Attorney-In-Fact 2022-04-14