The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ADC THERAPEUTICS SA SHS H0036K147   1,682,476 1,013,540 SH   SOLE   1,013,540 0 0
ALKERMES PLC SHS G01767105   9,886,092 356,384 SH   SOLE   356,384 0 0
ALKERMES PLC SHS G01767105   748,980 27,000 SH Put SOLE   27,000 0 0
ALLOGENE THERAPEUTICS INC COM 019770106   1,284,000 400,000 SH   SOLE   400,000 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107   5,742,300 30,000 SH Call SOLE   30,000 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106   4,489,500 75,000 SH   SOLE   75,000 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106   1,496,500 25,000 SH Call SOLE   25,000 0 0
APOGEE THERAPEUTICS INC COM 03770N101   15,006,378 537,093 SH   SOLE   537,093 0 0
ARAVIVE INC COM 03890D108   42,863 346,511 SH   SOLE   346,511 0 0
ARCELLX INC COMMON STOCK 03940C100   18,870,000 340,000 SH   SOLE   340,000 0 0
ARGENX SE SPONSORED ADR 04016X101   2,853,225 7,500 SH   SOLE   7,500 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101   2,519,000 20,000 SH   SOLE   20,000 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108   4,041,000 60,000 SH   SOLE   60,000 0 0
ASTRIA THERAPEUTICS INC COM 04635X102   11,262,451 1,466,465 SH   SOLE   1,466,465 0 0
AUTOLUS THERAPEUTICS PLC SPON ADS 05280R100   9,984,628 1,550,408 SH   SOLE   1,550,408 0 0
AVROBIO INC COM 05455M100   680,000 500,000 SH   SOLE   500,000 0 0
AXSOME THERAPEUTICS INC COM 05464T104   3,979,500 50,000 SH   SOLE   50,000 0 0
BIOHAVEN LTD COM G1110E107   893,065 20,866 SH   SOLE   20,866 0 0
BRIDGEBIO PHARMA INC NOTE 2.500% 3/1 10806XAB8   20,578,500 17,000,000 PRN   SOLE   17,000,000 0 0
BRIDGEBIO PHARMA INC COM 10806X102   3,229,600 80,000 SH   SOLE   80,000 0 0
CASSAVA SCIENCES INC COM 14817C107   2,723,710 121,000 SH Call SOLE   121,000 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202   15,864,000 400,000 SH   SOLE   400,000 0 0
CENTESSA PHARMACEUTICALS PLC SPONSORED ADS 152309100   6,334,003 795,729 SH   SOLE   795,729 0 0
CEREVEL THERAPEUTICS HLDNG I COM 15678U128   31,800,000 750,000 SH   SOLE   750,000 0 0
COHERUS BIOSCIENCES INC NOTE 1.500% 4/1 19249HAB9   3,403,157 6,000,000 PRN   SOLE   6,000,000 0 0
COMPASS PATHWAYS PLC SPONSORED ADS 20451W101   4,812,500 550,000 SH   SOLE   550,000 0 0
CONTEXT THERAPEUTICS INC COM 21077P108   371,563 328,817 SH   SOLE   328,817 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107   15,907,640 447,095 SH   SOLE   447,095 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107   3,355,194 94,300 SH Put SOLE   94,300 0 0
CULLINAN ONCOLOGY INC COM 230031106   3,057,000 300,000 SH   SOLE   300,000 0 0
CYMABAY THERAPEUTICS INC COM 23257D103   25,756,216 1,090,441 SH   SOLE   1,090,441 0 0
CYTOKINETICS INC COM NEW 23282W605   13,358,400 160,000 SH   SOLE   160,000 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201   4,194,000 300,000 SH   SOLE   300,000 0 0
ESTABLISHMENT LABS HLDGS INC COM G31249108   5,910,092 228,277 SH   SOLE   228,277 0 0
ESTABLISHMENT LABS HLDGS INC COM G31249108   5,825,250 225,000 SH Call SOLE   225,000 0 0
EYEPOINT PHARMACEUTICALS INC COM NEW 30233G209   7,397,511 320,100 SH Put SOLE   320,100 0 0
EYEPOINT PHARMACEUTICALS INC COM NEW 30233G209   2,539,789 109,900 SH   SOLE   109,900 0 0
FULCRUM THERAPEUTICS INC COM 359616109   843,750 125,000 SH   SOLE   125,000 0 0
IMMATICS N.V SHS N44445109   2,106,000 200,000 SH   SOLE   200,000 0 0
IMMATICS N.V W EXP 07/01/202 N44445117   546,636 187,204 SH   SOLE   187,204 0 0
IMMUNOGEN INC COM 45253H101   41,646,627 1,404,608 SH   SOLE   1,404,608 0 0
IMMUNOVANT INC COM 45258J102   14,534,850 345,000 SH   SOLE   345,000 0 0
INARI MED INC COM 45332Y109   1,298,400 20,000 SH   SOLE   20,000 0 0
INFLARX NV COM N44821101   326,158 200,097 SH   SOLE   200,097 0 0
INOZYME PHARMA INC COM 45790W108   8,033,517 1,885,802 SH   SOLE   1,885,802 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103   1,543,120 125,969 SH   SOLE   125,969 0 0
KRYSTAL BIOTECH INC COM 501147102   3,101,500 25,000 SH   SOLE   25,000 0 0
KURA ONCOLOGY INC COM 50127T109   2,754,273 191,535 SH   SOLE   191,535 0 0
LIANBIO SPONSORED ADS 53000N108   16,895,232 3,779,694 SH   SOLE   3,779,694 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105   23,138,000 100,000 SH   SOLE   100,000 0 0
MERSANA THERAPEUTICS INC COM 59045L106   2,320,000 1,000,000 SH   SOLE   1,000,000 0 0
MIRATI THERAPEUTICS INC COM 60468T105   5,877,879 100,049 SH   SOLE   100,049 0 0
MIRUM PHARMACEUTICALS INC COM 604749101   1,476,000 50,000 SH   SOLE   50,000 0 0
MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD 61559X104   4,286,965 70,988 SH   SOLE   70,988 0 0
MORPHIC HLDG INC COM 61775R105   1,232,310 42,670 SH   SOLE   42,670 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109   1,317,600 10,000 SH   SOLE   10,000 0 0
NEWAMSTERDAM PHARMA COMPANY ORDINARY SHARES N62509109   1,396,250 125,000 SH   SOLE   125,000 0 0
NEWAMSTERDAM PHARMA COMPANY W EXP 11/22/202 N62509117   428,810 137,000 SH   SOLE   137,000 0 0
NURIX THERAPEUTICS INC COM 67080M103   7,121,956 690,112 SH   SOLE   690,112 0 0
NUVALENT INC COM 670703107   12,878,250 175,000 SH   SOLE   175,000 0 0
NUVATION BIO INC COM CL A 67080N101   377,500 250,000 SH   SOLE   250,000 0 0
OMEROS CORP NOTE 5.250% 2/1 682143AG7   3,600,000 6,000,000 PRN   SOLE   6,000,000 0 0
PENUMBRA INC COM 70975L107   1,886,550 7,500 SH   SOLE   7,500 0 0
PROMIS NEUROSCIENCES INC COM NEW 74346M406   305,852 265,958 SH   SOLE   265,958 0 0
PUMA BIOTECHNOLOGY INC COM 74587V107   876,171 202,349 SH   SOLE   202,349 0 0
RELAY THERAPEUTICS INC COM 75943R102   3,303,000 300,000 SH   SOLE   300,000 0 0
ROCKET PHARMACEUTICALS INC W EXP 09/02/202 77313F114   36,750 75,000 SH   SOLE   75,000 0 0
ROIVANT SCIENCES LTD SHS G76279101   5,615,000 500,000 SH   SOLE   500,000 0 0
SAVARA INC COM 805111101   5,405,000 1,150,000 SH   SOLE   1,150,000 0 0
SPRINGWORKS THERAPEUTICS INC COM 85205L107   3,650,000 100,000 SH   SOLE   100,000 0 0
SPYRE THERAPEUTICS INC COM NEW 00773J202   11,137,762 517,554 SH   SOLE   517,554 0 0
STRUCTURE THERAPEUTICS INC SPONSORED ADS 86366E106   4,076,000 100,000 SH Call SOLE   100,000 0 0
TOURMALINE BIO INC COM 89157D105   1,782,361 68,081 SH   SOLE   68,081 0 0
TANGO THERAPEUTICS INC COM 87583X109   2,972,713 300,274 SH   SOLE   300,274 0 0
TERNS PHARMACEUTICALS INC COM 880881107   428,340 66,000 SH   SOLE   66,000 0 0
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS 881624209   19,836,000 1,900,000 SH   SOLE   1,900,000 0 0
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS 881624209   14,616,000 1,400,000 SH Call SOLE   1,400,000 0 0
VAXCYTE INC COM 92243G108   1,570,000 25,000 SH   SOLE   25,000 0 0
VERONA PHARMA PLC SPONSORED ADS 925050106   11,208,821 563,824 SH   SOLE   563,824 0 0
VIKING THERAPEUTICS INC COM 92686J106   5,583,000 300,000 SH   SOLE   300,000 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104   1,089,000 50,000 SH   SOLE   50,000 0 0
XENON PHARMACEUTICALS INC COM 98420N105   21,187,600 460,000 SH   SOLE   460,000 0 0