The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

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COLUMN 1COLUMN 2COLUMN 3COLUMN 4COLUMN 5COLUMN 6COLUMN 7COLUMN 8
VALUESHRS ORSH/PUT/INVESTMENTOTHERVOTING AUTHORITY
NAME OF ISSUERTITLE OF CLASSCUSIP(x$1000)PRN AMTPRNCALLDISCRETIONMANAGERSOLESHAREDNONE
ACCELERON PHARMA INCCOM00434H1086,90255,000SH SOLE 55,00000
ACHILLES THERAPEUTICS PLCSPONSORED ADS00449L10278380,000SH SOLE 80,00000
ACLARIS THERAPEUTICS INCCOM00461U1054,829275,000SH SOLE 275,00000
ACUTUS MED INCCOM0051111091,35880,000SH SOLE 80,00000
ALDEYRA THERAPEUTICS INCCOM01438T1062,266200,000SH SOLE 200,00000
ALNYLAM PHARMACEUTICALS INCCOM02043Q1074,23825,000SHCallSOLE 25,00000
APELLIS PHARMACEUTICALS INCCOM03753U10663210,000SH SOLE 10,00000
ARK ETF TRGENOMIC REV ETF00214Q30220,813225,000SHPutSOLE 225,00000
ARYA SCIENCES ACQU CORP IVCL AG316591087,504700,000SH SOLE 700,00000
ASCENDIS PHARMA A/SSPONSORED ADR04351P1012,63120,000SH SOLE 20,00000
AXSOME THERAPEUTICS INCCOM05464T1041,68725,000SH SOLE 25,00000
BCTG ACQUISITION CORPCOM05492W1031,138100,000SH SOLE 100,00000
BELLUS HEALTH INC NEWCOM NEW07987C204933300,000SH SOLE 300,00000
BRIDGEBIO PHARMA INCCOM10806X10233,528550,000SH SOLE 550,00000
BUTTERFLY NETWORK INCCOM CL A1241551021,448100,000SH SOLE 100,00000
CELLDEX THERAPEUTICS INC NEWCOM NEW15117B2021,67250,000SH SOLE 50,00000
CENTESSA PHARMACEUTICALS PLCSPONSORED ADS1523091001,48766,957SH SOLE 66,95700
CEREVEL THERAPEUTICS HLDNG ICOM15678U1285,124200,000SH SOLE 200,00000
CEREVEL THERAPEUTICS HLDNG I*W EXP 06/09/202015678U1021,04372,466SH SOLE 72,46600
CHARDAN HEALTHCR ACQSTN 2 COUNIT 99/99/999915957T20681975,000SH SOLE 75,00000
CHINOOK THERAPEUTICS INCCOM16961L1062,824200,000SH SOLE 200,00000
CULLINAN ONCOLOGY INCCOM2300311061,15945,000SH SOLE 45,00000
CUREVAC N VCOMN2451R10511,022150,000SHPutSOLE 150,00000
CURIS INCCOM NEW2312692005,246650,000SH SOLE 650,00000
CVRX INCCOM1266381052107,500SH SOLE 7,50000
CYCLACEL PHARMACEUTICALS INCCOM23254L6032,250380,000SH SOLE 380,00000
CYTOKINETICS INCCOM NEW23282W6051,38570,000SH SOLE 70,00000
CYTOMX THERAPEUTICS INCCOM23284F10547575,000SH SOLE 75,00000
ESSA PHARMA INCCOM NEW29668H7082,00070,000SH SOLE 70,00000
ESTABLISHMENT LABS HLDGS INCCOMG312491081,74720,000SH SOLE 20,00000
GALAPAGOS NVSPON ADR36315X1011,38720,000SH SOLE 20,00000
GLOBAL BLOOD THERAPEUTICS INCOM37890U10870020,000SH SOLE 20,00000
GOSSAMER BIO INCNOTE 5.000% 6/038341PAA01,6052,000,000PRN SOLE 2,000,00000
HARPOON THERAPEUTICS INCCOM41358P10669450,000SH SOLE 50,00000
HEALTH SCIENCES ACQ CORP 2ORD SHSG4411D1093,060300,000SH SOLE 300,00000
HORIZON THERAPEUTICS PUB LSHSG461881012,34125,000SH SOLE 25,00000
IMMATICS N.V*W EXP 07/01/2020N44445117654190,000SH SOLE 190,00000
IMMUNOVANT INCCOM45258J10231730,000SHCallSOLE 30,00000
INARI MED INCCOM45332Y1097,92985,000SH SOLE 85,00000
INTELLIA THERAPEUTICS INCCOM45826J1051,61910,000SH SOLE 10,00000
IONIS PHARMACEUTICALS INCCOM4622221002,99275,000SHCallSOLE 75,00000
IOVANCE BIOTHERAPEUTICS INCCOM4622601002,602100,000SH SOLE 100,00000
ITEOS THERAPEUTICS INCCOM46565G10464125,000SH SOLE 25,00000
KALVISTA PHARMACEUTICALS INCCOM4834971031,19850,000SH SOLE 50,00000
KURA ONCOLOGY INCCOM50127T1098,861425,000SH SOLE 425,00000
LIFESCI ACQUISITION II CORPCOM53229E1031,500150,000SH SOLE 150,00000
MACROGENICS INCCOM5560991092,14980,000SH SOLE 80,00000
MEDICUS SCIENCES ACQUISITIONCL A SHSG5960S1082,895300,000SH SOLE 300,00000
MEDICUS SCIENCES ACQUISITION*W EXP 02/12/2026G5960S1243433,333SH SOLE 33,33300
MEREO BIOPHARMA GROUP PLCADS5894921072,061650,000SH SOLE 650,00000
MERSANA THERAPEUTICS INCCOM59045L1061,15485,000SH SOLE 85,00000
MODERNA INCCOM60770K1072,93712,500SHCallSOLE 12,50000
MORPHIC HLDG INCCOM61775R10514,129246,201SH SOLE 246,20100
NANOSTRING TECHNOLOGIES INCCOM63009R10997215,000SH SOLE 15,00000
NAUTILUS BIOTECHNOLOGY INCCOM63909J1089,090900,000SH SOLE 900,00000
OCULAR THERAPEUTIX INCCOM67576A1003,545250,000SH SOLE 250,00000
PROTAGONIST THERAPEUTICS INCCOM74366E1026,288140,100SH SOLE 140,10000
PULMONX CORPCOM7458481012,64760,000SH SOLE 60,00000
QUANTUM SI INCCOM CL A74765K10592075,000SH SOLE 75,00000
RETROPHIN INCNOTE 2.500% 9/1761299AB25,9937,000,000PRN SOLE 7,000,00000
ROCKET PHARMACEUTICALS INCCOM77313F1065,315120,000SH SOLE 120,00000
SCHRODINGER INCCOM80810D1031,89025,000SH SOLE 25,00000
SPDR SER TRS&P BIOTECH78464A87027,080200,000SHPutSOLE 200,00000
SPRINGWORKS THERAPEUTICS INCCOM85205L1072,06025,000SH SOLE 25,00000
THE BEAUTY HEALTH COMPANY*W EXP 05/04/202688331L11628845,000SH SOLE 45,00000
VAXCYTE INCCOM92243G1081,12650,000SH SOLE 50,00000
VINCERX PHARMA INCCOM NEW92731L10610,890838,311SH SOLE 838,31100
ZENTALIS PHARMACEUTICALS INCCOM98943L1077,577142,418SH SOLE 142,41800
ZYMEWORKS INCCOM98985W1021,04130,000SH SOLE 30,00000