CONSOLIDATED BALANCE SHEETS (Unaudited) - USD ($) $ in Thousands	Mar. 31, 2023	Dec. 31, 2022
Current assets:
Cash and cash equivalents	$ 562,660	$ 248,329
Restricted cash	261	0
Investment securities, available-for-sale	909,761	875,715
Short-term investments, other	2,033	0
Accounts receivable	0	57
Prepaid expenses and other current assets	32,419	30,100
Deferred offering costs	625	568
Total current assets	1,507,759	1,154,769
Restricted cash, net of current portion	0	261
Right-of-use lease assets - operating, net	4,209	4,674
Property and equipment, net	3,721	3,201
Other non-current assets	479	429
Total assets	1,516,168	1,163,334
Current liabilities:
Accounts payable	476	2,379
Accrued expenses	22,694	29,285
Current portion of operating lease liability	2,067	2,282
Total current liabilities	25,237	33,946
Operating lease liability, net of current portion	2,692	3,046
Other non-current liabilities	104	104
Total liabilities	28,033	37,096
Commitments and Contingencies (Note 10)
Stockholders’ equity:
Preferred stock, $0.0001 par value; 10,000,000 shares authorized and 0 shares outstanding as of March 31, 2023 and December 31, 2022	0	0
Common stock, $0.0001 par value; 150,000,000 shares authorized as of March 31, 2023 and December 31, 2022; 37,398,019 and 34,473,905 shares issued and outstanding as of March 31, 2023 and December 31, 2022, respectively	4	3
Additional paid-in capital	2,151,527	1,693,732
Accumulated deficit	(661,781)	(564,207)
Accumulated other comprehensive loss	(1,615)	(3,290)
Total stockholders’ equity	1,488,135	1,126,238
Total liabilities and stockholders’ equity	$ 1,516,168	$ 1,163,334