X0306 4 2019-07-02 0 0001771917 Karuna Therapeutics, Inc. KRTX 0001727395 PureTech Health LLC 6 TIDE STREET BOSTON MA 02116 0 0 1 0 Common Stock 2019-07-02 4 C 0 5194800 A 5214798 D Common Stock 2019-07-02 4 C 0 1751704 A 6966502 D Common Stock 2019-07-02 4 C 0 428895 A 7395397 D Series Seed Preferred Stock 2019-07-02 4 C 0 4000000 D Common Stock 5194800 0 D Series A Preferred Stock 2019-07-02 4 C 0 1348814 D Common Stock 1751704 0 D Series B Preferred Stock 2019-07-02 4 C 0 330250 D Common Stock 428895 0 D The Series Seed Preferred Stock is convertible into shares of the Issuer's Common Stock on a 1.2987-for-one basis. Upon the closing of the Issuer's initial public offering, all shares of Series Seed Preferred Stock automatically converted into shares of Common Stock. The Series Seed Preferred Stock has no expiration date. The Series A Preferred Stock is convertible into shares of the Issuer's Common Stock on a 1.2987-for-one basis. Upon the closing of the Issuer's initial public offering, all shares of Series A Preferred Stock automatically converted into shares of Common Stock. The Series A Preferred Stock has no expiration date. The Series B Preferred Stock is convertible into shares of the Issuer's Common Stock on a 1.2987-for-one basis. Upon the closing of the Issuer's initial public offering, all shares of Series B Preferred Stock automatically converted into shares of Common Stock. The Series B Preferred Stock has no expiration date. /s/ Stephen M. Muniz 2019-07-02