Consolidated Statements of Cash Flows - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Operating activities:
Net loss	$ (182,627)	$ (255,099)	$ (166,000)
Adjustments to reconcile net loss to net cash provided by (used in) operating activities:
Stock-based compensation expense	140,749	166,950	136,848
Depreciation and amortization	35,879	35,512	25,368
Lease and asset impairment charges	3,054	9,845	0
Amortization of right-of-use assets	7,829	8,107	7,638
Realized loss on marketable securities	3	1,718	0
Other	523	427	1,957
Changes in operating assets and liabilities:
Accounts receivable	26,951	(10,613)	(18,948)
Inventory	(9,777)	7,871	(21,192)
Prepaid expenses and other current assets	(1,901)	(2,429)	(4,495)
Other noncurrent assets	(1,084)	(678)	925
Accounts payable	(3,354)	(6,017)	5,858
Accrued compensation and other related benefits	3,654	(2,637)	1,114
Deferred revenue	11,209	10,932	3,350
Accrued expenses and other current liabilities	(12,736)	28,301	3,336
Operating lease liability	(12,484)	(8,671)	(6,423)
Other noncurrent liabilities	776	1,284	(2,942)
Net cash provided by (used in) operating activities	6,664	(15,197)	(33,606)
Investing activities:
Proceeds from sales of marketable securities	3,856	100,191	49,117
Proceeds from maturities of marketable securities	25,782	82,825	18,528
Purchases of property and equipment	(12,393)	(48,601)	(131,661)
Purchase of intangible assets	(1,000)	(923)	0
Acquisition of business, net of cash acquired	0	0	(4,000)
Purchase of marketable securities	(48,876)	0	(282,871)
Net cash (used in) provided by investing activities	(32,631)	133,492	(350,887)
Financing activities:
Payments on technology license financing arrangement	0	(5,814)	(5,409)
Issuance of common stock from exercise of stock options and employee stock purchase plan purchases	10,914	19,483	21,226
Net cash provided by financing activities	10,914	13,669	15,817
Effect of exchange rate changes on cash, cash equivalents, and restricted cash	(164)	(33)	(44)
Net (decrease) increase in cash, cash equivalents, and restricted cash	(15,217)	131,931	(368,720)
Cash, cash equivalents, and restricted cash at beginning of year	359,284	227,353	596,073
Cash, cash equivalents, and restricted cash at end of year	344,067	359,284	227,353
Supplemental disclosures of cash flow information:
Cash paid for interest	0	436	841
Cash paid for taxes	5,641	4,927	3,925
Noncash investing and financing activities
Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities	1,351	3,324	26,750
Right-of-use assets obtained in exchange for new operating lease liabilities	$ 0	$ 6,518	$ 16,562