X0306 4 2021-08-02 0 0001770787 10x Genomics, Inc. TXG 0001189140 STUELPNAGEL JOHN R C/O 10X GENOMICS, INC. 6230 STONERIDGE MALL ROAD PLEASANTON CA 94588 1 0 0 0 Class A Common Stock 2021-08-02 4 S 0 1100 178.4759 D 390516 D Class A Common Stock 2021-08-02 4 S 0 1140 179.5341 D 389376 D Class A Common Stock 2021-08-02 4 S 0 960 180.3281 D 388416 D Class A Common Stock 2021-08-02 4 S 0 1100 181.4724 D 387316 D Class A Common Stock 2021-08-02 4 S 0 400 182.74 D 386916 D Class A Common Stock 2021-08-02 4 S 0 200 183.90 D 386716 D Class A Common Stock 2021-08-02 4 S 0 100 184.99 D 386616 D The sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person. This transaction was executed in multiple trades at prices ranging from $177.98 to $178.955. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price. This transaction was executed in multiple trades at prices ranging from $178.98 to $179.955. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price. This transaction was executed in multiple trades at prices ranging from $179.98 to $180.92. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price. This transaction was executed in multiple trades at prices ranging from $180.98 to $181.93. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price. This transaction was executed in multiple trades at prices ranging from $182.35 to $183.13. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price. This transaction was executed in multiple trades at prices ranging from $183.62 to $184.18. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price. /s/ Eric S. Whitaker, as Attorney-in-Fact 2021-08-04