X0306 4 2020-03-06 0 0001770787 10x Genomics, Inc. TXG 0001786720 Saxonov Serge C/O 10X GENOMICS, INC. 6230 STONERIDGE MALL ROAD PLEASANTON CA 94588 1 1 1 0 Chief Executive Officer Class A Common Stock 2020-03-06 4 M 0 8333 1.07 A 946347 D Class A Common Stock 2020-03-06 4 M 0 1667 1.20 A 948014 D Class A Common Stock 2020-03-06 4 S 0 1848 62.9126 D 946166 D Class A Common Stock 2020-03-06 4 S 0 3767 63.9132 D 942399 D Class A Common Stock 2020-03-06 4 S 0 1098 64.9121 D 941301 D Class A Common Stock 2020-03-06 4 S 0 800 65.785 D 940501 D Class A Common Stock 2020-03-06 4 S 0 600 66.86 D 939901 D Class A Common Stock 2020-03-06 4 S 0 618 68.1285 D 939283 D Class A Common Stock 2020-03-06 4 S 0 822 69.3429 D 938461 D Class A Common Stock 2020-03-06 4 S 0 447 70.0057 D 938014 D Stock Option (right to buy) 1.07 2020-03-06 4 M 0 8333 0.00 D 2026-11-18 Class A Common Stock 8333 33334 D Stock Option (right to buy) 1.20 2020-03-06 4 M 0 1667 0.00 D 2027-10-18 Class A Common Stock 1667 142083 D The option exercises and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person. This transaction was executed in multiple trades at prices ranging from $62.39 to $63.25. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price. This transaction was executed in multiple trades at prices ranging from $63.405 to $64.38. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price. This transaction was executed in multiple trades at prices ranging from $64.40 to $65.24. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price. This transaction was executed in multiple trades at prices ranging from $65.51 to $66.00. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price. This transaction was executed in multiple trades at prices ranging from $66.65 to $67.50. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price. This transaction was executed in multiple trades at prices ranging from $67.69 to $68.60. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price. This transaction was executed in multiple trades at prices ranging from $68.70 to $69.55. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price. This transaction was executed in multiple trades at prices ranging from $69.78 to $70.33. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price. This option, originally for 200,000 shares, of which 166,666 have been exercised, vested as to one-fourth of the shares on August 1, 2017, and one forty-eighth of the shares subject to the option vest each month thereafter, subject to the Reporting Person continuing as a service provider through each such date. This option, originally for 300,000 shares, of which 157,917 have been exercised, vested as to one-fourth of the shares on October 1, 2017, and one forty-eighth of the shares subject to the option vest each month thereafter, subject to the Reporting Person continuing as a service provider through each such date. /s/ Eric S. Whitaker, as Attorney-in-Fact 2020-03-09