X0306 4 2021-06-09 0001770141 UpHealth, Inc. UPH 0001866483 Balakrishnan Ramesh C/O UPHEALTH HOLDINGS, INC. 14000 S. MILITARY TRAIL #203 DELRAY BEACH FL 33484 true Co-Chief Executive Officer Common Stock 2021-06-09 4 A 0 4351175 A 4351175 D Received in exchange for 402,949 shares of UpHealth Holdings, Inc. ("Holdings") in connection with the merger of Holdings into a subsidiary of UpHealth, Inc. (the "Company") pursuant to the exchange ratio set forth in the business combination agreement between Holdings and the Company. The closing price of the Company's Common Stock on the effective date of the merger was $9.38. /s/ Julie D'Angelo, as attorney-in-fact for Ramesh Balakrishnan 2021-06-11