X0508 4 2024-01-31 0001770141 UpHealth, Inc. UPHL 0001451693 Katz Avi S 1731 EMBARCADERO ROAD, SUITE 200 PALO ALTO CA 94303 1 0 0 0 0 Common Stock 13886 D Common Stock 2024-01-31 4 A 0 100000 0.00 A 113886 D Common Stock 452430 I By GigAcquisitions2, LLC Includes Restricted Stock Units ("Prior RSUs") of UpHealth, Inc. (the "Company"), that are subject to vesting pursuant to previously disclosed vesting schedules. Subject to the Reporting Person's continued service to the Company, the Restricted Stock Units ("RSUs") shall vest on January 1, 2025; all RSUs shall immediately vest in the event of a Change of Control (as defined in the UpHealth, Inc. 2021 Equity Incentive Plan) of the Company. The Common Stock is held directly by GigAcquisitions2, LLC ("GigAcquisitions2"). The Common Stock held by GigAcquisitions2 is beneficially owned by Dr. Avi S. Katz, Chairman of the Board of Directors of the Company. Dr. Katz is the sole manager but is not a member of GigAcquisitions2 and, as a result, has sole voting and dispositive power over the shares held by GigAcquisitions2. /s/ Dr. Avi S. Katz 2024-02-02