X0508 4 2023-11-21 0001770141 UpHealth, Inc. UPH 0001451693 Katz Avi S 1731 EMBARCADERO ROAD, SUITE 200 PALO ALTO CA 94303 1 0 0 0 0 Common Stock 14166 D Common Stock 2023-11-21 4 S 0 280 0.40 D 13886 D Common Stock 452430 I By GigAcquisitions2, LLC Includes Restricted Stock Units ("RSUs") issued by UpHealth, Inc. (the "Company") that are subject to vesting pursuant to previously disclosed vesting schedules. The Common Stock is held directly by GigAcquisitions2, LLC (the "Sponsor"). The Common Stock, Private Warrants, and Private Rights held by the Sponsor are beneficially owned by Dr. Avi S. Katz, Chairman of the Board of Directors of the Company. Dr. Katz is also the Manager of the Sponsor, who has sole voting and dispositive power over the shares held by the Sponsor. /s/ Dr. Avi S. Katz 2023-11-22