Condensed Consolidated Statements of Stockholders' Equity (Unaudited) - USD ($) shares in Thousands, $ in Thousands	Total	At The Market Offering	Common Stock	Additional Paid-in Capital	Additional Paid-in Capital At The Market Offering	Accumulated Other Comprehensive Income (Loss)	Accumulated Deficit
Beginning balance at Dec. 31, 2021	$ 728,502		$ 18	$ 1,515,210		$ (1,366)	$ (785,360)
Beginning balance (in shares) at Dec. 31, 2021			184,929
Vesting of restricted stock			$ 1	(1)
Vesting of restricted stock (in shares)			1,419
Exercise of stock options	652			652
Exercise of stock options (in shares)			284
Stock-based compensation expense	7,755			7,755
Unrealized gain (loss) on marketable securities, net	(3,806)					(3,806)
Net income (loss)	(31,448)						(31,448)
Ending balance at Mar. 31, 2022	701,655		$ 19	1,523,616		(5,172)	(816,808)
Ending balance (in shares) at Mar. 31, 2022			186,632
Beginning balance at Dec. 31, 2022	$ 499,315		$ 19	1,558,459		(4,327)	(1,054,836)
Beginning balance (in shares) at Dec. 31, 2022	191,022		191,022
Fees incurred related to issuance of common stock from at the market offering		$ (200)			$ (200)
Vesting of restricted stock (in shares)			154
Exercise of stock options	$ 331			331
Exercise of stock options (in shares)	233		233
Stock-based compensation expense	$ 8,751			8,751
Unrealized gain (loss) on marketable securities, net	2,188					2,188
Net income (loss)	(82,123)						(82,123)
Ending balance at Mar. 31, 2023	$ 428,262		$ 19	$ 1,567,341		$ (2,139)	$ (1,136,959)
Ending balance (in shares) at Mar. 31, 2023	191,409		191,409