Maximum term for success payment.

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Estimated fair value of contingent consideration.

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Estimated fair value of Success payment liability.

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Gain expense in connection with change in estimated fair value of success payment liabilities.

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Maximum contingent consideration upon achievement of certain pre specified development milestones.

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Maximum potential success payments.

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Threshold market capitalization.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Percentage of voting equity interests acquired at the acquisition date in the business combination.

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Amount of increase (decrease) in the value of a contingent consideration liability, including, but not limited to, differences arising upon settlement.

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Amount of liability recognized arising from contingent consideration in a business combination, expected to be settled within one year or the normal operating cycle, if longer.

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Amount of liability recognized arising from contingent consideration in a business combination, expected to be settled beyond one year or the normal operating cycle, if longer.

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Amount of assets, excluding financial assets and goodwill, that lack physical substance, having a projected indefinite period of benefit, acquired at the acquisition date.

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Amount after accumulated impairment loss of an asset representing future economic benefits arising from other assets acquired in a business combination that are not individually identified and separately recognized.

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Total loss recognized during the period from the impairment of goodwill plus the loss recognized in the period resulting from the impairment of the carrying amount of intangible assets, other than goodwill.

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Acquisitions - Additional Information (Details) - USD ($)	1 Months Ended	3 Months Ended
	Feb. 28, 2019	Mar. 31, 2023	Mar. 31, 2022	Dec. 31, 2022
Business Acquisition [Line Items]
Goodwill		$ 140,627,000		$ 140,627,000
Estimated fair value of contingent consideration, short term liabilities		57,224,000		55,345,000
Estimated fair value of contingent consideration, long-term liabilities		98,615,000		95,034,000
Change in the estimated fair value of contingent consideration		5,460,000	$ (528,000)
Cobalt Biomedicine, Inc \| Acquisition Agreement
Business Acquisition [Line Items]
Business acquisition, percentage of voting interests acquired	100.00%
Goodwill	$ 140,600,000
Business acquisition, impairment of intangible assets or goodwill	0
Maximum contingent consideration upon achievement of certain pre-specified development milestones	$ 500,000,000.0
Maximum term for success payment	20 years
Cobalt Biomedicine, Inc \| Acquisition Agreement \| Research and Development Expense
Business Acquisition [Line Items]
Estimated fair value of contingent consideration		155,800,000		150,400,000
Estimated fair value of contingent consideration, short term liabilities		57,200,000		55,400,000
Estimated fair value of contingent consideration, long-term liabilities		98,600,000		95,000,000.0
Change in estimated fair value of success payment		4,800,000	46,800,000
Change in the estimated fair value of contingent consideration		5,500,000	$ 500,000
Cobalt Biomedicine, Inc \| Acquisition Agreement \| Long-term Liabilities \| Research and Development Expense
Business Acquisition [Line Items]
Estimated fair value of success payment liability		$ 14,300,000		$ 19,000,000.0
Cobalt Biomedicine, Inc \| Acquisition Agreement \| Minimum
Business Acquisition [Line Items]
Threshold market capitalization	$ 8,100,000,000
Cobalt Biomedicine, Inc \| Acquisition Agreement \| Market Capitalization Equal to or Exceeds $8.1 billion
Business Acquisition [Line Items]
Cobalt success payment	500,000,000.0
Cobalt Biomedicine, Inc \| Acquisition Agreement \| IPR&D
Business Acquisition [Line Items]
Business combination, intangible assets	$ 59,200,000