Organization - Additional Information (Details) - USD ($)	Mar. 31, 2023	Dec. 31, 2022	Aug. 31, 2022
Description Of Organization [Line Items]
Accumulated deficit	$ 1,136,959,000	$ 1,054,836,000
Cash, cash equivalents and marketable securities	355,100,000
Success payment liabilities	13,200,000
Contingent consideration	$ 104,600,000
Cowen | At The Market Offering
Description Of Organization [Line Items]
Common stock maximum aggregate offering price			$ 150,000,000.0