Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
OPERATING ACTIVITIES:
Net loss	$ (269,476)	$ (355,928)	$ (285,305)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation	15,625	11,070	5,921
Stock-based compensation expense	38,337	22,362	5,828
Change in the estimated fair value of contingent consideration	(3,364)	31,842	52,793
Change in the estimated fair value of success payment liabilities	(81,518)	26,031	72,142
Non-cash expense for operating lease right-of-use assets	12,106	6,844	4,250
Other non-cash items, net	(9,302)	(3,076)	233
Changes in operating assets and liabilities:
Prepaid expenses and other assets	(5,988)	(861)	(1,436)
Operating lease right-of-use assets and liabilities	1,562	5,088	91
Accounts payable	1,058	(266)	1,982
Accrued expenses and other liabilities	10,910	5,840	5,519
Net cash used in operating activities	(290,050)	(251,054)	(137,982)
INVESTING ACTIVITIES:
Purchases of marketable securities	(78,688)	(491,387)	(387,432)
Proceeds from maturities of marketable securities	310,126	280,025	158,741
Purchases of property and equipment	(20,876)	(29,862)	(23,872)
Other investing activities		(4,574)
Net cash provided by (used in) investing activities	210,562	(245,798)	(252,563)
FINANCING ACTIVITIES:
Proceeds from initial public offering, net of issuance costs		626,405
Proceeds from issuance of convertible preferred stock, net of issuance costs			435,538
Proceeds from employee stock purchase plan and exercise of stock options, net	4,312	5,346	149
Proceeds from at the market offering of common stock, net of issuance costs	601
Net cash provided by financing activities	4,913	631,751	435,687
Net (decrease) increase in cash, cash equivalents, and restricted cash	(74,575)	134,899	45,142
Cash, cash equivalents, and restricted cash at beginning of period	261,848	126,949	81,807
Cash, cash equivalents, and restricted cash at end of period	187,273	261,848	126,949
RECONCILITION OF CASH, CASH EQUIVALENTS AND RESTRICTED CASH:
Cash and cash equivalents	176,765	253,029	124,806
Restricted cash	6,100
Long-term restricted cash	4,408	8,819	2,143
Total cash, cash equivalents, and restricted cash	187,273	261,848	126,949
SUPPLEMENTAL CASH FLOW INFORMATION:
Operating lease right-of-use assets obtained in exchange for lease obligations	21,073	39,996	26,521
Purchases of property and equipment included in accounts payable and accrued liabilities	1,234	3,015	3,140
Cash received for amounts related to tenant improvement allowances	2,014	$ 5,445	$ 91
Remeasurement of operating lease right-of-use asset for lease modification	$ (12,801)