Income Taxes - Components of Net Deferred Tax Assets (Detail) - USD ($) $ in Thousands	Dec. 31, 2022	Dec. 31, 2021
Deferred tax assets:
Net operating loss carryforwards	$ 154,888	$ 114,368
Capitalized research and development	49,687
Tax credit carryforwards	44,051	24,008
Lease liabilities	28,050	25,754
Intangibles	7,949	5,986
Stock-based compensation	6,958	1,854
Accrued liabilities and allowances	6,807	4,401
Success payment liabilities	516	3,290
Other	155
Gross deferred tax assets	299,061	179,661
Valuation allowance	(274,348)	(156,622)
Deferred tax assets, net of valuation allowance	24,713	23,039
Deferred tax liabilities:
Right-of-use assets	(23,554)	(21,940)
Fixed assets	(1,159)	(1,050)
Other		(49)
Deferred tax liabilities	$ (24,713)	$ (23,039)