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Organization - Additional Information (Details) - USD ($)
$ / shares in Units, shares in Thousands
1 Months Ended 12 Months Ended
Feb. 28, 2021
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Aug. 31, 2022
Description Of Organization [Line Items]          
Stock-based compensation expense   $ 38,337,000 $ 22,362,000 $ 5,828,000  
Net proceeds from issuance of common stock   601,000      
Proceeds from public offering of common stock, net of offering costs     626,405,000    
Accumulated deficit   1,054,836,000 $ 785,360,000    
Cash, cash equivalents and marketable securities   434,000,000.0      
Success payment liabilities   18,600,000      
Contingent consideration   $ 99,100,000      
At The Market Offering | Common Stock          
Description Of Organization [Line Items]          
Issuance of common stock, net of offering costs (in shares)   149      
IPO | Common Stock          
Description Of Organization [Line Items]          
Issuance of common stock, net of offering costs (in shares) 27,000   27,025    
Common stock price per share $ 25.00        
Proceeds from public offering of common stock, net of offering costs $ 626,400,000        
Payments of underwriting discounts and commissions 45,200,000        
Offering expenses $ 4,000,000.0        
Underwriters' Option To Purchase Additional Shares | Common Stock          
Description Of Organization [Line Items]          
Issuance of common stock, net of offering costs (in shares) 3,500        
Cowen | At The Market Offering          
Description Of Organization [Line Items]          
Common stock maximum aggregate offering price         $ 150,000,000.0
Net proceeds from issuance of common stock   $ 600,000      
Portfolio Prioritization and Corporate Restructuring          
Description Of Organization [Line Items]          
Reduction workforce percentage   15.00%      
Expenses related to employee severance, benefits, and related costs   $ 6,800,000      
Stock-based compensation expense   $ 1,900,000